Results 81 to 90 of about 4,169,013 (222)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Convergence of Archimedean Copulas [PDF]

open access: yes
Convergence of a sequence of bivariate Archimedean copulas to another Archimedean copula or to the comonotone copula is shown to be equivalent with convergence of the corresponding sequence of Kendall distribution functions.No extra differentiability ...
Charpentier, A., Segers, J.J.J.
core  

Solution of Linear Radiative Transfer Equation in Hollow Sphere by Diamond Difference Discrete Ordinates and Decomposition Methods

open access: yesSemina: Ciências Exatas e Tecnológicas
In this article, we present a methodology to solve radiative transfer problems in spherical geometry without other forms of heat exchange. We use a decomposition method based on the Adomian formulations, together with a diamond difference scheme and a ...
Marcelo Schramm   +2 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

An Elementary Approach to Euler’s Reflection Formula and Its Role in the Infinite Product of the Sine Function and the Basel Problem

open access: yesFoundations
We present a proof, using elementary methods, of the Euler reflection formula for the Gamma function, based on an integral computed by Laplace and on the Euler–Gauss infinite product representation of Gamma.
Antonio E. Bargellini, Daniele Ritelli
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Existence and Stability Theorems for Implicit Neutral Fractional Integrodifferential Equations With Computational Results

open access: yesJournal of Function Spaces
This paper investigates a class of nonlinear implicit neutral integrodifferential equations involving Hilfer–Katugampola fractional operators, which provide an effective framework for describing dynamical systems with memory and hereditary properties. By
Manal Elzain Mohamed Abdalla   +2 more
doaj   +1 more source

Gaussian regressor-based adaptive control of exoskeleton joints in the presence of system uncertainty

open access: yesWearable Technologies
System uncertainty remains a challenge for effective control of lower extremity exoskeletons, particularly in clinical populations. Adaptive control offers a potential solution by accounting for unknown system characteristics in real time.
Mohamed Abdelhady, Thomas C. Bulea
doaj   +1 more source

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