Results 1 to 10 of about 100,444 (216)
On completable fuzzy metric spaces [PDF]
Fuzzy Sets and Systems, 2015 In this paper we construct a non-completable fuzzy metric space in the sense of George and Veeramani which allows to answer an open question related to continuity on the real parameter t. In addition, the constructed space is not strong (non-Archimedean).
Valentín Gregori +2 more
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Completing graphs to metric spaces [PDF]
Contributions to Discrete Mathematics, 2017 We prove that certain classes of metrically homogeneous graphs omitting triangles of odd short perimeter as well as triangles of long perimeter have the extension property for partial automorphisms and we describe their Ramsey expansions.
Andrés Aranda +7 more
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Completion of a Dislocated Metric Space [PDF]
Abstract and Applied Analysis, 2015 We provide a construction for the completion of a dislocated metric space (abbreviatedd-metric space); we also prove that the completion of the metric associated with ad-metric coincides with the metric associated with the completion of thed-metric.
Kumari, P. Sumati +3 more
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The metric completion of Outer Space [PDF]
Geometriae Dedicata, 2019 We develop the theory of a metric completion of an asymmetric metric space. We characterize the points on the boundary of Outer Space that are in the metric completion of Outer Space with the Lipschitz metric. We prove that the simplicial completion, the subset of the completion consisting of simplicial tree actions, is homeomorphic to the free ...
openaire +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source