Results 261 to 270 of about 294,629 (332)

Characterization of the complete mitochondrial genome of the rice bean (Vigna umbellata). [PDF]

BMC Plant Biol
Wu Y, Zhang K, Zhang B, Li Y, Liu G, Liang Z, Zhang J.   +6 more
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

The complete mitochondrial genome of Vaccinium oldhamii Miquel, a plant of the Ericaceae family. [PDF]

Mitochondrial DNA B Resour
Lee DH, Sim WH, Park CY, Kim DH, Kim JH, Kim HM, Che SH, Park WG, Na CS, Shim S.   +9 more
europepmc   +1 more source

Enhanced Blood‐Brain Barrier Penetrability of BACE1 SiRNA‐Loaded Prussian Blue Nanocomplexes for Alzheimer's Disease Synergy Therapy

Exploration, EarlyView.
BACE1 interfering RNA, metallothionein and ruthenium complexes ([Ru(bpy)2dppz]2+) were all loaded in prussian blue nanoparticles (PRM‐siRNA). PRM‐siRNA under near‐infrared light irradiation showed good photothermal effect and triggered instantaneous opening of blood‐brain barrier for enhanced drug delivery.
Xiaoyuan Ding, Yanyu Hu, Xiaotong Feng, Zekun Wang, Qile Song, Chunxue Dai, Bangjia Yang, Xiaoyan Fu, Dongdong Sun, Cundong Fan   +9 more
wiley   +1 more source

Complete Mitochondrial Genome of <i>Platygyra daedalea</i> and Characteristics Analysis of the Mitochondrial Genome in Merulinidae. [PDF]

Genes (Basel)
Jia S, Shen T, Cai W, Zhang J, Chen S.
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

The complete mitochondrial genome of Neobythites sivicola (Jordan & Snyder, 1901) (Ophidiiformes: Ophidiidae). [PDF]

Mitochondrial DNA B Resour
Song X, Zhang R, Zhang H, Li S, Ling J.
europepmc   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

The Complete Mitochondrial Genome of <i>Thymus mongolicus</i> and Its Phylogenetic Relationship with Lamiaceae Species. [PDF]

Biomolecules
Na N, Wu Z, Wang Z, Yang Y, Tian C, Zhu L, Ou T, Chen X, Xia H, Li Z.   +9 more
europepmc   +1 more source

Highly Targeted Metabolomics Coupled With Gene Expression Analysis by RT–qPCR Improves Beef Separation Based on Grass, Grain, or Grape Supplemented Diet

Food Frontiers, EarlyView.
ABSTRACT The objective of this study was to use a multi‐omics (i.e., gene expression quantification, metabolomics, and fatty acid [FA] profiling) approach to separate and authenticate beef from three different dietary groups. In this 2‐year study, Red Angus steers (n = 54) were randomly allocated to one of three treatments: (1) complex biodiverse ...
Lucas Krusinski, Chloe Castanon, Rosalee S. Hellberg, Isabella C. F. Maciel, Muhammad Ahsin, Stephan van Vliet, Jason E. Rowntree, Jenifer I. Fenton   +7 more
wiley   +1 more source