Results 231 to 240 of about 14,411,939 (297)

Validation of a Patient-Created, Patient-Reported Experience Measure for Inflammatory Bowel Disease in the United Kingdom. [PDF]

Health Expect
Guy Z, Hind D, Totton N, Sheldon E, Ezaydi N, Bursnall M, Lobo A.   +6 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Complete response to dual immune checkpoint blockade in a patient with Birt-Hogg-Dubé syndrome and epithelioid angiomyolipoma. [PDF]

J Immunother Cancer
Viola J, Cornish A, Carlo MI, Hamid A, Reuter VE, Russo P, Motzer RJ, Voss MH, Kotecha RR.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Impact of 4D-CT MIP reconstruction method on iGTV definition: A clinical case report. [PDF]

J Appl Clin Med Phys
Yu S, Pashtan I.
europepmc   +1 more source

The complete genome sequences of 2 species of African honeyguides (Indicatoridae, Piciformes). [PDF]

Biodivers Genomes
Kahindo C, Cisirika BM, Bapeamoni F, Charles BB, Fidel MS, Pirro S, Marks BD.   +6 more
europepmc   +1 more source

DNA-dependent protein kinase inhibition as a radiosensitizer in rectal cancer: toxicity must be evaluated in the context of organ preservation. [PDF]

J Gastrointest Oncol
Ravella R, Zambare W, Roth O'Brien D, Romesser PB.   +3 more
europepmc   +1 more source

Photodynamic Therapy in Central Serous Chorioretinopathy: Treatment Timing, Anatomical Response, and Recurrence in a Large Real-World Cohort. [PDF]

Ophthalmol Ther
Stüven CM, Herold T, Foerster P, Klaas J, Siedlecki J, Priglinger SG, Keidel LF, Schworm B.   +7 more
europepmc   +1 more source

Clinical and radiological outcomes following complete release of the long head of triceps in reverse shoulder arthroplasty. [PDF]

Shoulder Elbow
Kang HW, Italia K, Sane RM, Price RSM, Ingoe H, Maharaj J, Whitehouse SL, Gupta A.   +7 more
europepmc   +1 more source