Results 141 to 150 of about 1,456,287 (196)

Predictive factors associated with complete pathological response after neoadjuvant treatment for rectal cancer.

Cancer Radiothérapie, 2021
PURPOSE A proportion of 10 to 30% of patients treated by chemoradiotherapy followed by total mesorectal excision surgery for a locally advanced rectal cancer can achieve a complete pathological response. We aimed to identify predictive factors associated
J. Hajer, A. Rim, A. Ghorbel, Y. Amani, L. Ines, B. Asma, N. Chiraz   +6 more
semanticscholar   +1 more source

Predictors for complete pathological response for stage II and III rectal cancer following neoadjuvant therapy - A systematic review and meta-analysis.

American Journal of Surgery, 2020
BACKGROUND There has been an increasing interest in the complete pathological response (pCR) in rectal cancers following neoadjuvant therapy. The aim of this study was to identify predictive factors of pCR in locally advanced rectal cancer following ...
Yeqian Huang, Daniela Lee, C. Young
semanticscholar   +1 more source

Prediction of axillary pathologic response with breast pathologic complete response after neoadjuvant chemotherapy

Breast Cancer Research and Treatment, 2019
Many breast cancer patients receive sentinel lymph node biopsy after neoadjuvant chemotherapy (NAC). We evaluated the axillary pathologic complete response (pCR) in relation to achievement of breast pCR.We evaluated 1044 patients who were diagnosed with invasive breast cancer and were treated with NAC followed by curative surgery at the Samsung Medical
Hee Jun, Choi, Jai Min, Ryu, Isaac, Kim, Seok Jin, Nam, Seok Won, Kim, Jonghan, Yu, Jeong Eon, Lee, Se Kyung, Lee   +7 more
openaire   +2 more sources

Complete pathological response (pCR) in gastroesophageal cancer: Correlation with metabolic response

Cancer/Radiothérapie, 2020
Neoadjuvant chemoradiotherapy (nCRT) followed by surgery in patients with resectable esophageal or esophagogastric junctional (GEJ) (Siewert I) cancer is associated with long term overall survival benefits. Up to one third of all patients submitted to nCRT present pathological complete response (pCR). 18F-fluorodeoxyglucose positron emission tomography
Cabral, Francisco, Cruz, A., Casaca, R., Monteiro, C., Ramos, P., Pedro, C., Brandão, F., Fonseca, R., Ratão, P., Saldado, L., Pinto, Iola, Abecasis, N.   +11 more
openaire   +3 more sources

Complete pathologic response after preoperative rectal cancer chemoradiotherapy

ANZ Journal of Surgery, 2009
AbstractBackground:  Following preoperative treatment of rectal cancer with chemoradiotherapy (CRT), a complete pathological response (CPR) can be seen in the surgical specimen. The aim of this study was to assess the outcome of these patients as compared with those who did not have a complete response.Methods:  A retrospective study of the outcome of ...
Ciccocioppo, A., Stephens, J., Hewett, P., Rieger, N.   +3 more
openaire   +4 more sources

Characterization of pathologic complete response after preoperative chemoradiotherapy in carcinoma of the esophagus and outcome after pathologic complete response

Cancer, 2005
AbstractBACKGROUNDThe purpose of the current study was to test the hypothesis that a lower clinical TNM stage is associated with a higher rate of pathologic complete response (pathCR) in patients with esophageal carcinoma receiving preoperative chemoradiotherapy and to determine whether outcome after pathCR is related to clinical stage or treatment ...
Pooja, Rohatgi, Stephen G, Swisher, Arlene M, Correa, Tsung-T, Wu, Zhongxing, Liao, Ritsuko, Komaki, Garrett L, Walsh, Ara A, Vaporciyan, David C, Rice, Jack A, Roth, Jaffer A, Ajani   +10 more
openaire   +2 more sources

PD-L1 expression and Tumor mutation burden as Pathological response biomarkers of Neoadjuvant immunotherapy for Early-stage Non-small cell lung cancer: A systematic review and meta-analysis.

Critical reviews in oncology/hematology, 2022
To date, there is no approved biomarker for predicting pathological response in neoadjuvant programmed cell death (ligand) 1 (PD-(L)1) blockades treated early-stage non-small cell lung cancer (NSCLC).
H. Deng, Yi Zhao, Xiuyu Cai, Hualin Chen, B. Cheng, R. Zhong, Feng Li, S. Xiong, Jianfu Li, Jun Liu, J. He, W. Liang   +11 more
semanticscholar   +1 more source

Characteristics of pathologic complete response for locally advanced rectal cancer

The American Journal of Surgery, 2023
Neoadjuvant chemoradiation (NACRT) is the standard of care for locally advanced rectal cancers. The purpose of this study was to determine patient and tumor factors associated with a pathologic complete response (pCR).The National Surgical Quality Improvement Program proctectomy-targeted database was utilized to identify all patients from 2016 to 2020 ...
Adam J. Cloos, Makayla Schissel, Rishi Batra, Steven R. Donahue, Chelsea D. Wenos, Terrence Kumar, Jennifer A. Leinicke, Jon S. Thompson, Sean J. Langenfeld   +8 more
openaire   +2 more sources

Ultrasound-based deep learning radiomics in the assessment of pathological complete response to neoadjuvant chemotherapy in locally advanced breast cancer.

European Journal of Cancer, 2021
PURPOSE The aim of the study was to develop and validate a deep learning radiomic nomogram (DLRN) for preoperatively assessing breast cancer pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) based on the pre- and post-treatment ...
Meng Jiang, Chang‐Li Li, Xiao-Mao Luo, Zhirui Chuan, Wenzhi Lv, Xu Li, X. Cui, C. Dietrich   +7 more
semanticscholar   +1 more source

Pathological Complete Response in Neoadjuvant Treatment of Breast Cancer

Annals of Surgical Oncology, 2015
There has been recent interest in using pathological complete response (pCR) as a potential surrogate endpoint for long-term outcomes in the neoadjuvant treatment of high-risk, early-stage breast cancer.We review the clinical trials that have contributed to our understanding of the association between pCR and long-term outcomes, describe the various ...
Patricia, Cortazar, Charles E, Geyer
openaire   +2 more sources