Results 141 to 150 of about 6,430,501 (374)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Three models for gene assembly in ciliates: a comparison [PDF]

open access: yesComputer Science Journal of Moldova, 2010
We survey in this paper the main differences among three variants of an intramolecular model for gene assembly: the general, the simple, and the elementary models.
Miika Langille   +2 more
doaj  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Completely Distributive Complete Lattices [PDF]

open access: yesProceedings of the American Mathematical Society, 1952
openaire   +2 more sources

Difference sequence space m(M,ø,Ämn,p) F of fuzzy real numbers

open access: yesMathematical Modelling and Analysis, 2008
The difference sequence space m(M, ø, Äm n,p) F of fuzzy real numbers for both 1 ≤ p < 8 and 0
Binod Chandra Tripathy, Stuti Borgohain
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

L -Random and Fuzzy Normed Spaces and Classical Theory

open access: yesCubo, 2010
In this paper we study L-random and L-fuzzy normed spaces and prove open mapping and closed graph theorems for these spaces.En este artículo estudiamos espacios normados L-random and L-fuzzy.
DONAL O’REGAN, REZA SAADATI
doaj  

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