Results 271 to 280 of about 6,430,501 (374)

Emerging strategies to target metastasis and therapy resistance in melanoma

Molecular Oncology, EarlyView.
Emerging studies propose new approaches to interfere with melanoma progression. In recognition of melanoma awareness month, at Molecular Oncology, we highlight recently published research articles, focusing on novel therapeutic targets driving metastatic spread and outlining different strategies to overcome resistance to BRAF inhibitors and anti‐PD‐1 ...
Amel Aziba
wiley   +1 more source

Evaluation of Information Generated by ChatGPT on Preventing Peripheral Venous Catheter-Related Infections. [PDF]

Nurs Open
Pehlivan S, Akça Doğan D, Erbay Dallı Ö.   +2 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Interior design proposal for the Hulme F1 supercar : a written component completed in partial fulfilment of the requirements for the degree of Masters of Design at Massey University, College of Creative Arts, Wellington, New Zealand

, 2008
Kenneth Young
openalex   +1 more source

Mind the gap: underreporting of key compartments in endometriosis MRI with free-text and non-disease-specific templates. [PDF]

Insights Imaging
Deniffel C, Andreisek G, Burian E, Pauli E, Oelke M, Namdar K, Houbois C, Lutz A, Deniffel D.   +8 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Effect of an integrated intervention on the availability and completeness of Robson ten group classification system-related data in district hospitals in Bangladesh. [PDF]

J Glob Health
Hossain L, Hasan ASM, Mahmood HR, Azrin F, Ahmed A, Sayeed A, Jabeen S, Akter E, Murshid HB, Hassan AKMM, Rahman MM, Mallick T, Tonmon TT, Siddique MAB, Zaman S, Rasghuvanshi VS, Rahman A, Nadia N, Mahmud M, Alim MA, Rahman AE, Hoque DME, El Arifeen S.   +22 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Health data reporting challenges in public health facilities in the age of DHIS2: a mixed-methods study in the Teso sub-region of Uganda. [PDF]

BMC Health Serv Res
Lawrence MR, Fuller BP, Isabirye HK, Kyozira C, Makumbi I, Bakainaga A, Moore CC, Ssekitoleko R.   +7 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source