Results 31 to 40 of about 307,001 (266)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Domain-complete and LCS-complete Spaces

open access: yesElectronic Notes in Theoretical Computer Science, 2019
We study $G_δ$ subspaces of continuous dcpos, which we call domain-complete spaces, and $G_δ$ subspaces of locally compact sober spaces, which we call LCS-complete spaces. Those include all locally compact sober spaces-in particular, all continuous dcpos-, all topologically complete spaces in the sense of Čech, and all quasi-Polish spaces-in particular,
Matthew de Brecht   +3 more
openaire   +2 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

From G-Completeness to M-Completeness [PDF]

open access: yesSymmetry, 2019
The purpose of this paper is to obtain a sufficient condition for a G-Cauchy sequence to be an M-Cauchy sequence in fuzzy metric spaces. Our main result provides a partial answer to the open question posed by V. Gregori and A. Sapena. For application, we give a new fuzzy version of the Banach fixed point theorem.
Rachid Mecheraoui   +2 more
openaire   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

High Completeness and Accurate Reporting of Key Variables Make Data from the Danish Shoulder Arthroplasty Registry a Valuable Source of Information

open access: yesClinical Epidemiology, 2021
Jeppe Vejlgaard Rasmussen,1,2 Anders El-Galaly,3– 5 Theis Muncholm Thillemann,6 Steen Lund Jensen3– 5 1Department of Orthopaedic Surgery, Herlev-Gentofte Hospital, Copenhagen, Denmark; 2Department of Clinical Medicine, University of ...
Rasmussen JV   +3 more
doaj  

Complete mergeability and amodal completion

open access: yesActa Psychologica, 1999
When image fragments are taken to correspond to the visible portions of a single occluded object, the object is said to 'amodally complete' behind the occluder. Kellman and Shipley (Kellman, P. J., & Shipley, T. F. (1991). A theory of visual interpolation in objective perception.
openaire   +3 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

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