Results 71 to 80 of about 307,001 (266)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Theoretical Computer Science, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Pre-symmetric c-distances and characterization of complete cone metric spaces
Applied General TopologyThe main goal of this research is to express the definition of pre-symmetric c-distances in cone metric spaces inspired by pre-symmetric w-distances defined by Romaguera and Tirado [Mathematics. 12 (2024), 2:305] and give the properties of this type of c-
Seyedeh Sara Karimizad +1 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Complete and Symmetrically Complete Families of Distributions
The Annals of Statistics, 1987 The paper presents a variety of results of the type ``completeness implies symmetric completeness''. Symmetric completeness of order k of a family of probability measures means that the family of k th powers of the probability measures is complete for the family of symmetric functions.
Mandelbaum, Avi, Ruschendorf, Ludger
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Evaluating the completeness of electronic health records in dental education: a big data study
Frontiers in Oral HealthObjectivesThe BigMouth Dental Data Repository is an oral health database developed from de-identified electronic health record (EHR) data from eleven dental schools within the United States.
Tamanna Tiwari +6 more
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Hybrid Deduction–Refutation Systems
Axioms, 2019 Hybrid deduction–refutation systems are deductive systems intended to derive both valid and non-valid, i.e., semantically refutable, formulae of a given logical system, by employing together separate derivability operators for each of these and combining
Valentin Goranko
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
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