Results 71 to 80 of about 167,596,152 (287)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and elaboration [PDF]

, 2007
Much medical research is observational. The reporting of observational studies is often of insufficient quality. Poor reporting hampers the assessment of the strengths and weaknesses of a study and the generalisability of its results. Taking into account
Egger, Matthias, Douglas G Altman, Mulrow, Cynthia D, Cynthia D Mulrow, Charles Poole, Gøtzsche, PC, Altman, Douglas G, Pocock, SJ, von Elm, Erik, Schlesselman, JJ, Altman, DG, Stuart J Pocock, Von Elm, E, Altman, Douglas G., Mulrow, Cynthia D., STROBE, Initiative, Egger, M, James J Schlesselman, Gøtzsche, Peter C., Schlesselman, James J, Matthias Egger, STROBE Initiative, Mulrow, CD, Vandenbroucke, Jan P, Pocock, Stuart J, Poole, Charles, Vandenbroucke, Jan P., Erik von Elm, Gøtzsche, Peter C, Jan P Vandenbroucke, Elm, Erik von, Vandenbroucke, JP, Poole, C, Pocock, Stuart J., Schlesselman, James J., Peter C Gøtzsche   +35 more
core   +4 more sources

Complete Sacral Agenesis. A Case Report.

The Kurume Medical Journal, 1991
We report a case of a girl with complete sacral agenesis associated with arthrogrypotic-like deformity. This case demonstrates that a posterior knee release and braces following operation are effective treatment for knee-flexion contractures. Accordingly it is suggested that a supracondylar osteotomy is not required for mild or moderate recurrence of ...
T, Okuno, A, Inoue, R, Sakai
openaire   +3 more sources

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Completeness of malaria indicator data reporting via the District Health Information Software 2 in Kenya, 2011–2015

Malaria Journal, 2017
Background Health facility-based data reported through routine health information systems form the primary data source for programmatic monitoring and evaluation in most developing countries.
Sophie Githinji, Robinson Oyando, Josephine Malinga, Waqo Ejersa, David Soti, Josea Rono, Robert W. Snow, Ann M. Buff, Abdisalan M. Noor   +8 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Clinical practice guidelines for neonatal therapeutic hypothermia across European Society for Paediatric and Neonatal Intensive Care (ESPNIC) member countries: a multidisciplinary blind comparison

The Lancet Regional Health. Europe
Summary: Background: Therapeutic hypothermia (TH) decreases mortality and neuro-developmental disability in neonates greater or equal than 36 weeks’ gestation with moderate-to-severe hypoxic-ischaemic encephalopathy (HIE) due to perinatal asphyxia. TH is
Daniele De Luca, Costanza Neri, Almudena Alonso-Ojembarrena, Mariachiara Ippolito, Anna Milan, Marco Piastra, Manuel Sanchez-Luna, Karl F. Schettler, Anna Zanin, Tullio Ghi, Andrea Cortegiani   +10 more
doaj   +1 more source

Registration bias in a clinical quality register

Endoscopy International Open, 2019
Background and aims The quality of medical quality registers is poorly defined and lack of trust in data due to low completeness may be a major barrier against their use in quality improvement interventions. The aim of the current observational study was
Geir Hoff, Thomas de Lange, Michael Bretthauer, Stein Dahler, Fred-Arne Halvorsen, Gert Huppertz-Hauss, Ole Høie, Øystein Kjellevold, Volker Mortiz, Per Sandvei, Birgitte Seip, Øyvind Holme   +11 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source