Results 191 to 200 of about 4,051,827 (361)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

APHRON-BASED DRILLING FLUIDS: SOLUTION FOR LOW PRESSURE RESERVOIRS

open access: yesRudarsko-geološko-naftni Zbornik, 2009
Drilling wells throughout depleted or low pressure reservoirs requires low density drilling fluids, often with density less than water. Methods to reduce the density of drilling fluids have included mixing-in air or nitrogen. However, problems with these
Nediljka Gaurina-Međimurec   +1 more
doaj  

Binary Matrix Completion Under Diameter Constraints [PDF]

open access: green, 2020
Tomohiro Koana   +2 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Complete Multipliers [PDF]

open access: yesTransactions of the American Mathematical Society, 1972
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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