Results 191 to 200 of about 112,380 (334)

A novel analytical approach to design horizontal well completion using ICDs to eliminate heel-toe effect. [PDF]

Sci Rep
Eivazi R.
europepmc   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source

Use of deep learning and self-supervised methods to accelerate and improve the earth subsurface characterization. [PDF]

Sci Rep
Simoes V.
europepmc   +1 more source

Key Technologies for well Drifting， Scraping and Flushing in Single-Trip Operation of Coiled Tubing in Deep Shale Gas Wells

Shiyou jixie
To address the issue of cumbersome， long-period and costly conventional drifting， pipe scraping and flushing operation after drilling with oil-based mud in deep shale gas wells， a technical solution with "single-trip" coiled tubing operation as the core ...
Liu Zhiyao, Guan Bin, Liu Jialin, Yin Congbin, Li Jun, Ren Neng   +5 more
doaj  

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Optimal on-off scheduling for intermittent pumping wells under grid-connected pv systems. [PDF]

Sci Rep
Qiao M, Ren F, Li Y, Jia D.
europepmc   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Mechanism, Application, and Prospect of Fracturing-Flooding Technology: A Review. [PDF]

ACS Omega
Zhang H, Fan M, Wu J, An X, Xu Y, Gan B, Guo S, Hu W.   +7 more
europepmc   +1 more source

Shale gas extraction in the UK: a review of hydraulic fracturing [PDF]

, 2012
Bickle, M., Goodman, D., Koppelman, B., Mair, R., Roberts, J., Selley, R., Shipton, Z., Thomas, H., Walker, A., Woods, E., Younger, P.   +10 more
core  

High‐Efficiency CO2 Electrolysis Enabled by Interface‐Engineered Composite Electrolytes in Ni‐Based SOEC

Advanced Science, EarlyView.
This study addresses the critical issue of delamination between YSZ and GDC electrolytes in SOECs, which is caused by Thermal deformation disparity. A novel YSZ‐GDC composite interlayer, fabricated using a simple dip‐coating method, is introduced to solve this problem. This layer effectively suppresses delamination by mitigating thermal stress.
Rustam Yuldashev, Hyunchul Jung, Ji Hoon Park, Jin Hee Lee, Min‐Chul Kim   +4 more
wiley   +1 more source