Results 151 to 160 of about 239,856 (283)
Advanced Science, EarlyView.Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang +16 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a hybrid quantum‐classical framework for accurate prediction of protein structures on utility‐level quantum processors. We evaluate the practical application of the Variational Quantum Eigen‐solver (VQE) in protein structure prediction and demonstrate its superiority over state‐of‐the‐art deep learning methods in molecular docking ...
Yuqi Zhang +10 more
wiley +1 more source
Research and Application of MultiNode Intelligent Completion Technology
Shiyou jixie, 2016 Uneven production along the long horizontal section could result in premature water or gas breakthrough.Inflow control devices (ICD) are usually applied between the isolation packers to adjust the production profile of isolated well section.The ICD ...
Dang Wenhui +4 more
doaj
The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer
Advanced Science, EarlyView.In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu +16 more
wiley +1 more source
Application of the K341 Long Rubber Packer in Casing Damaged Well for Water Layer Isolation
Shiyou jixie, 2017 Aiming at the problems encountered in Changqing Oilfield inseriously corrosive casing damaged well that the conventional packer for water layer isolation has a short service period and difficult to be set after multiple isolation operation, based on the ...
Luo Yougang +5 more
doaj
Advanced Science, EarlyView.Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl +12 more
wiley +1 more source
Research and Application of Through-Tubing Coiled Tubing Nitrogen Foam Flushing Technology
Shiyou jixieWhen ø38.1 mm （1.5 in） coiled tubing is used to flush sand settled in the casing of low-pressure well through completion tubing， the limited injection rate leads to low flow rate of sand washing fluid in the casing， difficulty in carrying sand， and ...
Wang Jingang +3 more
doaj
Advanced Science, EarlyView.The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan +13 more
wiley +1 more source
Purse string contracture with complete anterior capsular phimosis
Indian Journal of Ophthalmology - Case Reports, 2021 Shruthy V Ramesh +3 more
openaire +1 more source
AI‐Driven Acceleration of Fluorescence Probe Discovery
Advanced Science, EarlyView.We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang +18 more
wiley +1 more source