Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
A sustainable spectrofluorimetric method for ivabradine quantification based on erythrosin B quenching with quantum mechanical modeling and Box-Behnken design optimization. [PDF]
RSC AdvAlqahtani AS +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Transvenous lead extraction: predictors of procedure complexity. [PDF]
Open HeartCsillik A +9 more
europepmc +1 more source
Advancing Systemic Risk Assessment for Complex, Interdependent Systems: A Research Agenda. [PDF]
Risk AnalLogan T +9 more
europepmc +1 more source
The CsFT-FD complex controls flowering by regulating <i>CsAP1</i> and <i>CsLFY</i> in saffron. [PDF]
GM Crops FoodXi X +6 more
europepmc +1 more source
In-silico screening of anti-cancer natural compounds targeting NF-κB as identification of potential therapeutic inhibitor. [PDF]
In Silico PharmacolTasnim J +9 more
europepmc +1 more source
The Importance of Plastic Surgery in Multidisciplinary Teams: A Systematic Review and Meta-analysis of Comparative Studies. [PDF]
Plast Reconstr Surg Glob OpenElemosho A +6 more
europepmc +1 more source