Results 191 to 200 of about 73,478 (259)

3D organotypic skin models recapitulate autoantibody-driven pemphigus pathomechanisms and targeted therapeutic response. [PDF]

Sci Adv
Zhai H, Jin X, Moghaddam AO, Spieker MF, Seiffert-Sinha K, Sinha AA, Yang R, Meng F.   +7 more
europepmc   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Bioengineered Tricomposite Hydrogel Enhances Chondrogenic Phenotype and Hyaline Matrix Formation in Human Chondrocytes. [PDF]

Gels
Rojas-Murillo A, de la Garza-Kalife DA, Lara-Arias J, Leija-Gutiérrez H, Franco-Márquez R, Morales-Wong DL, Vilchez-Cavazos F, Garza-Treviño EN, Simental-Mendía M.   +8 more
europepmc   +1 more source

Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic gut-on-a-chip model [PDF]

, 2020
Alvarado, David M., Bajinting, Adam, Binkley, Michael M., Ciorba, Matthew A., Gazit, Vered, George, Steven C., Goo, William H., Good, Misty, Guo, Jun, Ismail, Usama, Iticovici, Micah, King, Cristi R., Lanik, Wyatt E., Luke, Cliff J., Meacham, J. Mark, Ou, Jocelyn, Rubin, Deborah C., Seiler, Kristen M., Stappenbeck, Thaddeus, Swietlicki, Elzbieta A., Traore, Mahama A., VanDussen, Kelli L., Warner, Brad W.   +22 more
core   +1 more source

Application Strategies of Bone Marrow Mesenchymal Stromal Cells in Bone‐Related Diseases

Cell Proliferation, EarlyView.
Engineered BMSCs and vesicles enhance therapy effects for bone diseases via multi‐strategic approaches. ABSTRACT Bone‐related diseases (e.g., osteoporosis, osteoarthritis and fractures) exhibit a rising global incidence, imposing significant burdens on both quality of life and healthcare systems.
Xuemei Long, Dan Tan, Qianke Tao, Qiaonan Ye, Luwen Ye, Qing Li, Jingang Xiao   +6 more
wiley   +1 more source

Plasma Fibronectin Drives Macrophage Elongation via Integrin β3-Tie2 Axis in Blood Clots. [PDF]

Cancers (Basel)
Knowles LM, Eichler H, Pilch J.
europepmc   +1 more source

Mechanobiology in Stem Cell‐Based Bioprinting

Cell Proliferation, EarlyView.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source

Bioconvergence of sound-guided and supramolecular assembly strategies to create peptide-protein composite hydrogels with predictable shape-to-function features. [PDF]

Mater Today Bio
Ligorio C, Cianciosi A, Tognato R, Natta M, Parolini R, Ardicli S, Babayev H, Sapjanskaite I, Kilgour SL, Homer R, Pramanik B, Zhou Z, Malandrino A, Priglinger E, Akdis C, Stoddart MJ, Mata A, Serra T.   +17 more
europepmc   +1 more source

Equine experimental lameness induction models

Equine Veterinary Education, EarlyView.
Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley   +1 more source