Results 51 to 60 of about 73,478 (259)

Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]

, 2009
Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
Atrasheuskaya, Alena, Bukin, Eugenij, Friedl, Peter, Gröger, Marion, Hofer-Warbinek, Renate, Ignatyev, George, Knapp, Sylvia, Matt, Ulrich, Pasteiner, Waltraud, Petzelbauer, Peter, Reingruber, Sonja, Zacharowski, Kai, Zinkl, Daniela   +12 more
core  

A two-compartment mechanochemical model of the roles of\ud transforming growth factor β and tissue tension in dermal wound healing [PDF]

, 2011
The repair of dermal tissue is a complex process of interconnected phenomena, where cellular, chemical and mechanical aspects all play a role, both in an autocrine and in a paracrine fashion.
Hall, C. L., Maini, P. K., McCue, S. W., McElwain, D. L. S., Murphy, K. E.   +4 more
core   +3 more sources

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source

Changes in various forms of fibronectin in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass – a prospective, observational study

Scientific Reports
Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) is associated with the transient activation of a systemic inflammatory response.
Anna Lemańska-Perek, Dorota Krzyżanowska-Gołąb, Grzegorz Wysoczański, Barbara Barteczko-Grajek, Waldemar Goździk, Barbara Adamik   +5 more
doaj   +1 more source

Enhanced Detection of Desmoplasia by Targeted Delivery of Iron Oxide Nanoparticles to the Tumour-Specific Extracellular Matrix

Pharmaceutics, 2021
Diagnostic imaging of aggressive cancer with a high stroma content may benefit from the use of imaging contrast agents targeted with peptides that have high binding affinity to the extracellular matrix (ECM).
Meenu Chopra, Jiansha Wu, Yen Ling Yeow, Louise Winteringham, Tristan D. Clemons, Martin Saunders, Venkata Ramana Kotamraju, Ruth Ganss, Kirk W. Feindel, Juliana Hamzah   +9 more
doaj   +1 more source

Controlled Delivery of Sdf-1 Alpha and Igf-1: Cxcr4(+) Cell Recruitment and Functional Skeletal Muscle Recovery [PDF]

, 2015
Therapeutic delivery of regeneration-promoting biological factors directly to the site of injury has demonstrated its efficacy in various injury models.
Farrar, Roger P., Hammers, David W., Hsieh, Pei-Ling, Merscham-Banda, Melissa, Pham, Chantal B., Rybalko, Viktoriya Y., Suggs, Laura J.   +6 more
core   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

PRF a novel acumen for managing post-surgical defects after removal of mandibular third molars: A case report

Journal of Head & Neck Physicians and Surgeons, 2015
Platelet-rich fibrin (PRF) or leucocyte- and platelet-rich fibrin (L-PRF) is a second-generation PRP where autologous platelets and leucocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue.
Aruna Tambuwala, Deepak Kaul, Tofiq Bohra, Shehzad Sheikh   +3 more
doaj  

Fabrication and Characterization of Quad-Component Bioinspired Hydrogels to Model Elevated Fibrin Levels in Central Nervous Tissue Scaffolds

Gels
Multicomponent interpenetrating polymer network (mIPN) hydrogels are promising tissue-engineering scaffolds that could closely resemble key characteristics of native tissues.
Ana M. Diaz-Lasprilla, Meagan McKee, Andrea C. Jimenez-Vergara, Swathisri Ravi, Devon Bellamy, Wendy Ortega, Cody O. Crosby, Jennifer Steele, Germán Plascencia-Villa, George Perry, Dany J. Munoz-Pinto   +10 more
doaj   +1 more source

Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]

, 2017
Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S, Kim, Oleg V, Litvinov, Rustem I, Weisel, John W   +3 more
core   +2 more sources