Results 151 to 160 of about 2,172,394 (315)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Gene 33/Mig6/ERRFI1, an Adapter Protein with Complex Functions in Cell Biology and Human Diseases. [PDF]
Xu D, Li C.
europepmc +1 more source
This course is an introduction to complex analysis, or the theory of the analytic functions of a complex variable. Put differently, complex analysis is the theory of the differentiation and integration of functions that depend on one complex variable ...
The Saylor Foundation
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Phylogenetic and developmental analyses indicate complex functions of calcium-activated potassium channels in zebrafish embryonic development. [PDF]
Silic MR, Black MM, Zhang G.
europepmc +1 more source
Problems arising from the study of holomorphic continuation and holomorphic approximation have been central in the development of complex analysis in finitely many variables, and constitute one of the most promising lines of research in infinite ...
Mujica, Jorge
core
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Volume Dimension of Mass Functions in Complex Networks
A novel definition of volume dimension for a mass function based on a sigmoid asymptote is proposed; in particular, we extend the volume dimension of a mass function to define the volume dimensions for nodes and edges in complex networks.
Maria del Carmen Soto-Camacho +3 more
doaj +1 more source
Protein kinase PIM2: A simple PIM family kinase with complex functions in cancer metabolism and therapeutics. [PDF]
Wang Y, Xiu J, Ren C, Yu Z.
europepmc +1 more source
Correlations between Maxwell's multipoles for Gaussian random functions on the sphere
Maxwell's multipoles are a natural geometric characterization of real functions on the sphere (with fixed ⌊). The correlations between multipoles for Gaussian random functions are calculated by mapping the spherical functions to random polynomials.
Dennis, MR +3 more
core +1 more source

