Cofilin-1 is a redox-sensitive guard of the NLRP3 inflammasome. [PDF]
Park YH +6 more
europepmc +1 more source
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier +12 more
wiley +1 more source
Histological architecture of the intersphincteric region of the anal canal: implications for the anatomical basis of anal fistula pathways. [PDF]
Muro S, Nakajima Y, Nimura A, Akita K.
europepmc +1 more source
High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello +5 more
wiley +1 more source
Atlanto-occipital assimilation: the role of ex-, basi-, and suboccipital bones in the physiopathology of type I basilar invagination. Patient series. [PDF]
Maciel TMM, Botelho RV.
europepmc +1 more source
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah +13 more
wiley +1 more source
A Transient Two-Phase Productivity Forecasting Method in Fractured Nanoporous Shale Gas Reservoirs. [PDF]
Zhang R, He S, Zhang Q, Xiao H, Zhang L.
europepmc +1 more source
Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker +14 more
wiley +1 more source
Calmodulin assists during co-translational folding of the K<sub>V</sub>7.2 channel calcium responsive domain. [PDF]
Muguruza-Montero A +10 more
europepmc +1 more source

