CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleenâtargeted expression, providing greater applications for ...
Eshan A. Narasipura +4 more
wiley +1 more source
Automated elucidation of crystal and electronic structures in boron nitride from X-ray absorption spectra using uniform manifold approximation and projection. [PDF]
Hasegawa R +9 more
europepmc +1 more source
Almost optimal geometrically local quantum LDPC codes in any dimension. [PDF]
Li X, Lin TC, Wills A, Hsieh MH.
europepmc +1 more source
Information Geometry-Based Two-Stage Track-Before-Detect Algorithm for Multi-Target Detection in Sea Clutter. [PDF]
Liu J, Wu H, Yang Z, Hua X, Cheng Y.
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A Psychoacoustic Feature Extraction and Spatio-Temporal Analysis Framework for Continuous Aircraft Noise Monitoring. [PDF]
He T, Hou J, Chen D.
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A novel paradigm for single-cell annotation in stem cell research. [PDF]
Atkeson T +6 more
europepmc +1 more source
Geometry-preserving vector field reconstruction of high-dimensional cell-state dynamics using ddHodge. [PDF]
Maehara K, Ohkawa Y.
europepmc +1 more source

