Results 41 to 50 of about 500,277 (264)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Sparse Algorithm for Computing the DFT Using Its Real Eigenvectors

open access: yesSignals, 2021
Direct computation of the discrete Fourier transform (DFT) and its FFT computational algorithms requires multiplication (and addition) of complex numbers.
Rajesh Thomas   +2 more
doaj   +1 more source

Noise-enhanced computation in a model of a cortical column [PDF]

open access: yes, 2005
Varied sensory systems use noise in order to enhance detection of weak signals. It has been conjectured in the literature that this effect, known as stochastic resonance, may take place in central cognitive processes such as the memory retrieval of ...
Gerstner, Wulfram, Mayor, Julien
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Analysis of algorithms performing basic arithmetic operations in the quadratic RNS

open access: yesНаука. Инновации. Технологии, 2022
In this paper we explore the question of representing complex numbers in a residue number system and build algorithms for the operations of addition and multiplication. The idea of the construction of such systems is in determining how the set of complex
Lyudmila Borisovna Kopytkova
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Difficulties in Complex Multiplication and Exponentiation [PDF]

open access: yes, 2010
During my study of the iteration of functions of the form $f(z)=z^{\alpha}+c$, where $z,c \in \mathbbC$, and $\alpha$ is a rational non-integer larger than 2 (\cite{s1}), I encountered a fundamental difficulty in the exponentiation of a complex number ...
Sasmor, Joshua C.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

From Holonomy of the Ising Model Form Factors to n-Fold Integrals and the Theory of Elliptic Curves

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2007
We recall the form factors $f^(j)_{N,N}$ corresponding to the $lambda$-extension $C(N,N; lambda)$ of the two-point diagonal correlation function of the Ising model on the square lattice and their associated linear differential equations which exhibit ...
Salah Boukraa   +3 more
doaj  

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