Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Cortical functional connectivity and topology based on complex network graph theory analysis during acute pain stimuli. [PDF]
Luo Y, Du J, Fang F, Shi P.
europepmc +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Time to focus again on matrix metalloproteinases? Results of complex network analysis involving the pathophysiology of HER2-positive breast cancer. [PDF]
Buiar PG +3 more
europepmc +1 more source
Critical complex network structures in animal gastrointestinal tract microbiomes. [PDF]
Ma ZS, Shi P.
europepmc +1 more source
Understanding the complex network of anxiety, depression, sleep problems, and smartphone addiction among college art students using network analysis. [PDF]
Luo J, Xu J, Lin Y, Chen Q.
europepmc +1 more source
A novel social-network-analysis-based approach for analyzing complex network of actors involved in accessibility of anti-cancer medications in Iran. [PDF]
Lankarani KB +3 more
europepmc +1 more source
Understanding the complex network of objectively assessed cognition and self-reported psychological symptoms in people with multiple sclerosis. [PDF]
van Dam M +8 more
europepmc +1 more source
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