Results 41 to 50 of about 1,340,789 (232)
Editorial: Bridging Scales and Levels [PDF]
Network Neuroscience, 2018 Network neuroscience strives to understand the networks of the brain on all spatiotemporal scales and levels of observation. Current experimental and theoretical capabilities are beginning to facilitate a more holistic perspective, uniting these networks.
Emma K. Towlson +1 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Strategic behavior of large language models and the role of game structure versus contextual framing
Scientific ReportsThis paper investigates the strategic behavior of large language models (LLMs) across various game-theoretic settings, scrutinizing the interplay between game structure and contextual framing in decision-making.
Nunzio Lorè, Babak Heydari
doaj +1 more source
Abstract and Applied Analysis, 2014 We discuss the delay-independent asymptotic stability of Caputo type fractional-order neutral differential systems with multiple discrete delays.
Hai Zhang, Daiyong Wu, Jinde Cao
doaj +1 more source
Complex networks with complex weights
Physical Review E17 pages, 7 figures, 1 ...
Lucas Böttcher, Mason A. Porter
openaire +3 more sources
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
An Adaptive Multi-Homogeneous Sensor Weight Calculation Method for Body Sensor Networks
IEEE Access, 2019 In the Body Sensor Networks (BSNs), a comprehensive and intuitive conclusion can be obtained by analyzing the physiological state in the mode of multi-heterogeneous source fusion. However, if a node in the sensing layer fails, the input-oriented analysis
Han Shi +4 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source