Results 161 to 170 of about 1,570,755 (283)

Numerical simulation for the free surface flow around a complex ship hull form at different Froude numbers

, 2011
Yasser M. Ahmed
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Introducingg Complex Numbers into Basic Growth Functions (1) : Applying Complex Representation of '1' to Differentiation of Exponential Function with Base e Expanded into Infinite Series [PDF]

, 2004
Masataka Shimojo, Yoki Asano, Kentarou Ikeda, Reiko Ishiwaka, Minako Eguchi, Hiroyuki Sato, Manabu Tobisa, Yutaka Nakano, Noriko Ohba, Yasuhira Masuda   +9 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Hyper-Complex Numbers in Physics

, 2015
Vlad L. Negulescu
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Mechanosensory Subgenual Organ Complex in the Stick Insect Bacillus rossius (Phasmatodea): Neuroanatomy and Functional Morphology. [PDF]

J Comp Neurol
Strauß J, Rühr PT.
europepmc   +1 more source

Space and Geometry Irrational Numbers and their Representation by Sequences and Series Auslese aus meiner Unterrichts- und Vorlesungspraxis Leçons de Géométrie supérieure La Géométrie analytique génerale N H Abel: sa Vie et son uvre Theory of the Algebraic Functions of a Complex Variable Recherches sur l'Élasticité

, 1907
G. H. B.
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Spatial and Temporal Trends in the Invasion Dynamics of the Ring-Necked Parakeet (Psittacula krameri) in the Urban Complex of Thessaloniki, Greece. [PDF]

Animals (Basel)
Thoma CT, Makridou KN, Bakaloudis DE.
europepmc   +1 more source