Results 261 to 270 of about 12,782,893 (295)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Induction of high numbers of T_reg cells post treatment with anti-IL-2/IL-2 complex associates with alleviation of experimental psoriasis-like skin inflammation. [PDF]

BMC Immunol
Salman S, Khalil SM, Abdel-Latif AM, El Attar YA, Salem ML.   +4 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

An integrated neutrosophic Z-numbers based CRITIC-EDAS decision model for smart solar panel evaluation in sustainable energy planning. [PDF]

Sci Rep
Abbas MZ, Anjum R, Hussain A, Ahmad M, Haleemzai I.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Direct Identification and Quantification of Flavonoids and Their Structural Isomers Using Ambient Ionization Tandem Mass Spectrometry. [PDF]

Rapid Commun Mass Spectrom
Wang Y, Xu L, Gu T, Li H, Chen DDY.
europepmc   +1 more source

The coherent structures of EVP fluid flow past a circular cylinder. [PDF]

Theor Comput Fluid Dyn
Corrochano A, Iqbal KT, Parvar S, Le Clainche S, Tammisola O.   +4 more
europepmc   +1 more source

Dagger categories and the complex numbers: Axioms for the category of finite-dimensional Hilbert spaces and linear contractions

Matthew Di Meglio, Chris Heunen
openalex   +2 more sources

Exogenous hormones regulate the sequentially reproductive output in Pseudostellaria heterophylla with a chasmogamous-cleistogamous mixed mating system. [PDF]

Sci Rep
Sun Q, Wu L, Zhao JM, Zhang YW.
europepmc   +1 more source

Hidden in plain sight: commonly used copper N-heterocyclic carbene catalysts gain stabilization from anagostic Cu⋯H-C interactions. [PDF]

Chem Sci
Yan C, Chang T, Chen YS, Paterson AL, McElheny D, Mankad NP.   +5 more
europepmc   +1 more source