Results 51 to 60 of about 55,344 (203)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Teaching Complex Numbers in High School
One of the mathematics standards for high schools stated in the Common Core State Standards Initiative (CCSS, 2010 Appendix A, p. 60) is the understanding of the Complex Number system, performing arithmetic operations with complex numbers, representing ...
Chavez, Esperanza Gotoman
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
DISTRIBUTION OF COMPLEX ALGEBRAIC NUMBERS
Götze F, Kaliada D, Zaporozhets D. DISTRIBUTION OF COMPLEX ALGEBRAIC NUMBERS. PROCEEDINGS OF THE AMERICAN MATHEMATICAL SOCIETY. 2017;145(1):61-71.For a region Omega subset of C denote by Psi(Q; Omega) the number of complex algebraic numbers in Omega of ...
Kaliada, Dzianis +2 more
core +1 more source
Knowledge about complex analysis, complex numbers and exponents and logarithmsRaise complex numbers to higher and higher powers. Experiment to see how the norm affects whether the powers converge to the origin or move away from itComponente Curricular ...
Schreiber, Michael
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Knowledge about complex analysis, complex numbers and exponents and logarithmsRaise complex numbers to higher and higher powers. Experiment to see how the norm affects whether the powers converge to the origin or move away from itComponente Curricular ...
Schreiber, Michael
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

