Results 81 to 90 of about 12,782,893 (295)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Axiomatic of Fuzzy Complex Numbers

open access: yesAxioms, 2012
Fuzzy numbers are fuzzy subsets of the set of real numbers satisfying some additional conditions. Fuzzy numbers allow us to model very difficult uncertainties in a very easy way.
Angel Garrido
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

New Approach to Neutrosophic Numbers and Neutrosophic Complex Numbers

open access: yesAxioms
In this study, we introduced non-Newtonian neutrosophic numbers and non-Newtonian neutrosophic complex numbers by combining two recently popular approaches and examined some of their properties.
Abdullah Dertli, Ceremnur Tetik
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hardware realizations of arithmetic with complex integer numbers on PLD-base [PDF]

open access: yesTekhnologiya i Konstruirovanie v Elektronnoi Apparature, 2008
Hardware realizations of arithmetic with complex integer numbers were proposed. The generators of sine and cosine with different frequency were used to make behavior stand.
Opanasenko V. N.   +2 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Parabolic Numbers: A New Perspective

open access: yesJournal of New Theory
Thus far, many studies have been conducted on $p$-complex numbers. Depending on the sign of $p$, there are three cases: hyperbolic, dual, and elliptic. In the literature, dual numbers are called parabolic numbers, but they do not parameterize parabolas ...
Furkan Semih Dündar
doaj   +1 more source

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