Results 41 to 50 of about 49,724 (264)

Progress towards understanding the genetics of posttraumatic stress disorder

, 2014
Posttraumatic stress disorder (PTSD) is a complex syndrome that occurs following exposure to a potentially life threatening traumatic event. This review summarises the literature on the genetics of PTSD including gene–environment interactions (GxE ...
Morris, Charles P., Voisey, Joanne, Lawford, Bruce R., Young, Ross McD.   +3 more
core   +1 more source

Genetics and epigenetics of memory functions : from nematodes to human health and disease [PDF]

, 2012
Identifying the molecular mechanisms that underlie learning and memory is one of the major challenges in neuroscience. Synapses are highly specialized intercellular junctions specialized for transmission of signals between neuron and its target cells ...
Vukojević, Vanja
core   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

A Global Prospective Harmonization Framework for Suicidality, Anhedonia, and Obsessive‐Compulsive Symptoms in Psychiatric Genetic Studies: A Cross‐Continental Study Within the Ancestral Population Network

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT This study aims to prospectively collect harmonized, quantitative, and dimensional psychiatric phenotypes (suicidality, anhedonia, and obsessive‐compulsive symptoms) and information on discrimination, stigma, and unfair treatment in up to 27,500 individuals across diverse ancestries and clinical populations for genetic analysis within the NIMH
Ana M. Diaz‐Zuluaga, Jacey L. Anderberg, Ana M. Ramirez‐Diaz, Andrea Horvath Marques, Catherine E. Rast, Daniel Bustamante, Deborah Jonker, Johanna Valencia‐Echeverry, Joseph Kyebuzibwa, Josselyn S. Muñoz, Kristien van der Walt, Mauricio Castaño Ramirez, Olivia Wootton, Renee M. Frederick, Rocky E. Stroud II, Ruben Gur, Sang Jin Rhee, Shaili C. Jha, Stella Gichuru, Susan Service, Victor I. Reus, Akena Dickens, Carlos Lopez‐Jaramillo, Carrie E. Bearden, Dan J. Stein, Ezra S. Susser, James J. Crowley, Jonathan Flint, Kenneth S. Kendler, Lukoye Atwoli, Michele T. Pato, Nelson B. Freimer, Roel A. Ophoff, Yong Min Ahn, Loes Olde Loohuis, Eric A. Storch, Bizu Gelaye   +36 more
wiley   +1 more source

Cannabis-assisted psychotherapy for complex dissociative posttraumatic stress disorder: A case report

Frontiers in Psychiatry, 2023
BackgroundA dissociative subtype of posttraumatic stress disorder, known as “D-PTSD”, has been included in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.
Anya Ragnhildstveit, Anya Ragnhildstveit, Anya Ragnhildstveit, Miriam Kaiyo, Miriam Kaiyo, Matthew Brian Snyder, Laura Kate Jackson, Alex Lopez, Chasity Mayo, Alyssa Claire Miranda, Alyssa Claire Miranda, River Jude August, River Jude August, Paul Seli, Reid Robison, Reid Robison, Lynnette Astrid Averill, Lynnette Astrid Averill, Lynnette Astrid Averill, Lynnette Astrid Averill   +19 more
doaj   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Stressors, coping and symptoms of adjustment disorder in the course of the COVID-19 pandemic – study protocol of the European Society for Traumatic Stress Studies (ESTSS) pan-European study

European Journal of Psychotraumatology, 2020
Background During the current COVID-19 pandemic, the people in Europe are exposed to self-isolation, quarantine, job loss, risk of contracting COVID-19, or grief of loved ones. Such a complex array of stressors may lead to symptoms of adjustment disorder
Annett Lotzin, Elena Acquarini, Dean Ajdukovic, Vittoria Ardino, Maria Böttche, Kristina Bondjers, Maria Bragesjö, Małgorzata Dragan, Piotr Grajewski, Margarida Figueiredo-Braga, Odeta Gelezelyte, Jana Darejan Javakhishvili, Evaldas Kazlauskas, Matthias Knefel, Brigitte Lueger-Schuster, Nino Makhashvili, Trudy Mooren, Luisa Sales, Aleksandra Stevanovic, Ingo Schäfer   +19 more
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Differential predictors of DSM-5 PTSD and ICD-11 complex PTSD among African American women

European Journal of Psychotraumatology, 2017
Background: Complex posttraumatic stress disorder (CPTSD) is proposed for inclusion in the ICD-11 as a diagnosis distinct from posttraumatic stress disorder (PTSD), reflecting deficits in affective, self-concept, and relational domains.
Abigail Powers, Negar Fani, Sierra Carter, Dorthie Cross, Marylene Cloitre, Bekh Bradley   +5 more
doaj   +1 more source

POSTTRAUMATIC STRESS SYMPTOMS IN EMERGENCY SERVICE AMBULANCE PERSONNEL

Social Work/Maatskaplike Werk, 2005
A diversity of research has demonstrated that, although all people will present with a reaction after a traumatic incident, only a minority will develop posttraumatic stress disorder PTSD (Allan, La Grange, Niehaus, Scheurkogel & Stein, 1998).
Jackie Stewart, Leslie Swartz
doaj   +1 more source