Results 111 to 120 of about 13,765,551 (318)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Idempotent vector spaces and their linear transformations
Concrete OperatorsThis article extends topics about linear algebra and operator theoretic linear transformations on complex vector spaces to those on bicomplex spaces.
Johnston William, Wahl Rebecca G.
doaj +1 more source
Complex interpolation of weighted noncommutative $L_p$-spaces
, 2009 Let $\mathcal{M}$ be a semifinite von Neumann algebra equipped with a semifinite normal faithful trace $\tau$. Let $d$ be an injective positive measurable operator with respect to $(\mathcal{M}, \tau)$ such that $d^{-1}$ is also measurable.
Ricard, Éric, Xu, Quanhua
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Complex crowns of Riemannian symmetric spaces and non-compactly causal symmetric spaces
, 2001 In this paper we define a distinguished boundary for the complex crowns $\Xi\subeq G_\C /K_\C$ of non-compact Riemannian symmetric spaces $G/K$. The basic result is that affine symmetric spaces of $G$ can appear as a component of this boundary if and ...
Gindikin, Simon, Kroetz, Bernhard
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Abstract and Applied Analysis, 2013 We introduced the ideal convergence of generalized difference sequence spaces combining an infinite matrix of complex numbers with respect to λ-sequences and the Musielak-Orlicz function over n-normed spaces.
Awad A. Bakery
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source