Results 111 to 120 of about 8,195,688 (291)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Effect of disconnector and high-voltage conductor on propagation characteristics of PD-induced UHF signals

open access: yesHigh Voltage, 2018
UHF (ultra high frequency) method has been widely used in PD (partial discharge) detection for its high sensitivity. The resonance, distortion, and attenuation appearing in the propagation process of UHF signals in GIS (gas insulated switchgear) will ...
Minxia Shi   +8 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Some Remarks on Existence of a Complex Structure on the Compact Six Sphere

open access: yesAxioms
The existence or nonexistence of a complex structure on a differential manifold is a central problem in differential geometry. In particular, this problem on S6 was a long-standing unsolved problem, and differential geometry is an important tool ...
Daniel Guan, Na Li, Zhonghua Wang
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Affinity Propagation Clustering Using Path Based Similarity

open access: yesAlgorithms, 2016
Clustering is a fundamental task in data mining. Affinity propagation clustering (APC) is an effective and efficient clustering technique that has been applied in various domains.
Yuan Jiang, Yuliang Liao, Guoxian Yu
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Distribution Analysis of Complexes Using the Optimization of Thermodynamic Model

open access: yesJournal of MMIJ
Various chemical reactions are utilized in the metallurgical industry, such as electrorefining, ion-exchange, solvent extraction, and so on. Identifying the materials involved is essential for a proper understanding of chemical reactions.
Masahito UCHIKOSHI
doaj   +1 more source

A Family of Complex Nilmanifolds with in finitely Many Real Homotopy Types

open access: yesComplex Manifolds, 2018
We find a one-parameter family of non-isomorphic nilpotent Lie algebras ga, with a > [0,∞), of real dimension eight with (strongly non-nilpotent) complex structures.
Latorre Adela   +2 more
doaj   +1 more source

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