Results 81 to 90 of about 13,893,592 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analytical modeling of rotor-structure coupling using modal decomposition for the structure and the blades. [PDF]

open access: yes, 2014
This paper presents a linear semi-analytical model that is able to predict complex rotor-structure coupling phenomena and their stability. It was primarily designed so as to gain a better physical understanding of this kind of aeroelastic instabilities ...
ROUCOULES, Lionel   +3 more
core  

Hybrid Reliability-Based Design Optimization of Complex Structures With Random and Interval Uncertainties Based on ASS-HRA

open access: yesIEEE Access, 2019
In this paper, an efficient hybrid reliability analysis (HRA) method and a hybrid reliability-based design optimization (HRBDO) approach are proposed for realistic complex engineering structures with random and interval uncertainties.
Jin Cheng   +5 more
doaj   +1 more source

The Structure and Function of Complex Networks [PDF]

open access: yesSIAM Review, 2003
Inspired by empirical studies of networked systems such as the Internet, social networks, and biological networks, researchers have in recent years developed a variety of techniques and models to help us understand or predict the behavior of these systems.
openaire   +2 more sources

Computational complexity in electronic structure [PDF]

open access: yesPhys. Chem. Chem. Phys., 2013
In quantum chemistry, the price paid by all known efficient model chemistries is either the truncation of the Hilbert space or uncontrolled approximations. Theoretical computer science suggests that these restrictions are not mere shortcomings of the algorithm designers and programmers but could stem from the inherent difficulty of simulating quantum ...
Whitefield, James D.   +2 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Ion-Selective Sensors for Orthopaedic Applications: A Systematic Review

open access: yesBiosensors
Sensors are an established driver of diagnostics and prevention in the medical field, including orthopaedics. Today, the subclass of ion-selective sensors (ISSs) is on the leading edge due to its advantages, enabled by technological advancements in ...
Giorgia Polidori   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Structure and complexity of relational queries [PDF]

open access: yesJournal of Computer and System Sciences, 1980
AbstractThis paper is an attempt at laying the foundations for the classification of queries on relational data bases according to their structure and their computational complexity. Using the operations of composition and fixpoints, a Σ-π hierarchy of height ω2, called the fixpoint query hierarchy, is defined, and its properties investigated.
Ashok K. Chandra, David Harel
openaire   +4 more sources

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