Results 71 to 80 of about 3,687,194 (237)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Version [2.0.0]-[ENTIRETY—sEmanNTIc pRovisioning and govErning ioT devices in smart energY domain]
SoftwareXENTIRETY 1 is a web application for governing and provisioning IoT devices. Due to the rapid evolution and digitization of energy systems, energy domain ontology is required to manage the data in a structured way.
Zhiyu Pan +2 more
doaj +1 more source
IEEE Access, 2019 In [1], the calculation of (8) was erroneous. To be specific, as shown in (8) of [1], the average transmit power of a specially-designed signal ${x_{m} = - {{\sqrt {P_{S}} {h_{Sm}}h_{Am}^{*}{x_{S}}}}/{{{{\left |{ {{h_{Am}}} }\right |}^{2}}}}}$ was ...
Ming Sun, Yulong Zou, Jia Zhu
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Remote Sensing, 2019 The space information networks (SIN) have a series of characteristics, such as strong heterogeneity, multiple types of resources, and difficulty in management.
Xiangli Meng, Lingda Wu, Shaobo Yu
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Design, Modeling, and Vibration Control of a Damper Based on Magnetorheological Fluid and Elastomer
ActuatorsThe aim of this study is to propose a damper based on magnetorheological (MR) fluid and elastomer for application in vehicle engine mounting systems to dissipate the vibration energy transferred from the engine to the vehicle body.
Zhuang Jin +4 more
doaj +1 more source