Results 231 to 240 of about 33,755,974 (386)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

An Ion Exchange Study of Anionic Complexes in the Zinc Thiosulfate System. [PDF]

, 1972
Hans Persson, Stig R. Johansson, J. Krogh-Moe, Ole Ra, Sigfrid Svensson   +4 more
openalex   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

COMPLEX SYSTEM DESIGN EXPOSURE THROUGH A SATELLITE DESIGN COMPETITION

, 1969
Dario Schor, Kane Anderson, Cody Friesen, Kris Goodmanson, Morgan May, A. Darbandi, Witold Kinsner, Ron Britton, Malcolm Symonds   +8 more
openalex   +2 more sources

A Norm Condition for Disconjugacy of Complex Differential Systems [PDF]

, 1972
Shui-Nee Chow, Pui-Kei Wong
openalex   +1 more source

Understanding complex systems through differential causal networks. [PDF]

Sci Rep
Defilippo A, Giorgi FM, Veltri P, Guzzi PH.   +3 more
europepmc   +1 more source

Retracted: Secure Complex Systems: A Dynamic Model in the Synchronization. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Complex brain networks: graph theoretical analysis of structural and functional systems

Nature Reviews Neuroscience, 2009
E. Bullmore, O. Sporns
semanticscholar   +1 more source

A complex systems approach to mosaic loss of the Y chromosome. [PDF]

Geroscience
Guo X, Dai X.
europepmc   +1 more source