Results 241 to 250 of about 33,755,974 (386)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Molecular Pharmacological Studies on Drug-Receptor Complexes System in Drug Action. II. The Mode of Action of Parathion on an Acetylcholine Receptor.

, 1963
Masayasu Kimura, Toshiji Igarashi, Sadao Iwashita   +2 more
openalex   +2 more sources

Spectrophotometric Study of the Complex Equilibria in Palladium-Chromeazurol S System [PDF]

, 1972
SUKUMAR MANDAL, TEJ SINGH, ARUN K. DEY
openalex   +1 more source

Generative learning for forecasting the dynamics of high-dimensional complex systems. [PDF]

Nat Commun
Gao H, Kaltenbach S, Koumoutsakos P.
europepmc   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Action of the Murine Toxin of Pasteurella pestis on Enzyme Complexes of the Electron Transport System

, 1966
Solomon Kadis, Samuel J. Ajl
openalex   +1 more source

Thinking about inequalities in physical activity as an emergent feature of complex systems. [PDF]

Int J Behav Nutr Phys Act
Jones SM, Porroche-Escudero A, Shearn K, Hunter RF, Garcia L.   +4 more
europepmc   +1 more source

A complex systems approach to obesity: a transdisciplinary framework for action. [PDF]

Perspect Public Health, 2023
Griffiths C, Radley D, Gately P, South J, Sanders G, Morris MA, Clare K, Martin A, Heppenstall A, McCann M, Rodgers J, Nobles J, Coggins A, Cooper N, Cooke C, Gilthorpe MS, Ells L.   +16 more
europepmc   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Copolymerization of Polar Vinyl Monomers and Olefins with a Complex Catalyst System

, 1968
Noboru Yamazaki, Seiken MAEDA
openalex   +2 more sources