Results 111 to 120 of about 5,765,386 (368)

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Unraveling cradle-to-grave disease trajectories from multilayer comorbidity networks

open access: yesnpj Digital Medicine
We aim to comprehensively identify typical life-spanning trajectories and critical events that impact patients’ hospital utilization and mortality. We use a unique dataset containing 44 million records of almost all inpatient stays from 2003 to 2014 in ...
Elma Dervić   +7 more
doaj   +1 more source

Adaptive Output Feedback Control for Uncertain Nonlinear Systems Subject to Deferred State Constraints

open access: yesIEEE Access
This paper addresses the tracking control problem for a class of uncertain nonlinear systems with full state deferred constraints. The constraints considered occur after a period of system operation rather than from the beginning.
Li Guan, Lijie Wang, Yang Liu
doaj   +1 more source

Comparison of certain complexes of modules of generalized fractions and Cech complexes [PDF]

open access: yesarXiv, 2005
We establish an explicit quasi-isomophism of complexes, which is homogeneous in graded situation, from a given Cech complex of modules of generalized fractions.
arxiv  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The Penrose Transform for Complex Projective Space [PDF]

open access: yesarXiv, 2008
Various complexes of differential operators are constructed on complex projective space via the Penrose transform, which also computes their cohomology.
arxiv  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Tsallis entropy of complex networks [PDF]

open access: yesarXiv, 2015
How complex of the complex networks has attracted many researchers to explore it. The entropy is an useful method to describe the degree of the $complex$ of the complex networks. In this paper, a new method which is based on the Tsallis entropy is proposed to describe the $complex$ of the complex networks.
arxiv  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy