Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Performance analysis of device discovery algorithms for D2D communication
The device-to-device (D2D) communication is a candidate technology to implement 5G standards commercially.To initiate D2D, device discovery is a primary issue and very few algorithms have been proposed for device discovery. A discovery algorithm has many
Hayat, Omar +2 more
core +1 more source
An Algorithm Architecture for Radio Interferometric Data Processing
We present a foundational, scalable algorithm architecture for processing data from aperture synthesis radio telescopes. The analysis leading to the architecture is rooted in the theory of aperture synthesis, signal processing, and numerical optimization,
S. Bhatnagar +4 more
doaj +1 more source
The article presents a study of the computational complexity and efficiency of various parallel algorithms that implement the numerical solution of the equation in the hereditary α(t)-model of radon volumetric activity (RVA) in a storage chamber.
Dmitrii Tverdyi
doaj +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Boundary SPH for Robust Particle–Mesh Interaction in Three Dimensions
This paper introduces an algorithm to tackle the boundary condition (BC) problem, which has long persisted in the numerical and computational treatment of smoothed particle hydrodynamics (SPH).
Ryan Kim, Paul M. Torrens
core +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Comparative Analysis of some Low-Complexity Blind Synchronization Algorithms for IR-UWB Systems
International audienceUltra wideband (UWB) radio has emerged as anattractive candidate for short-range wireless communicationsin recent years due to its unique features.
Azou, Stéphane +2 more
core +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source

