Results 61 to 70 of about 915,821 (290)

Managing Web Service Interface Complexity via an OO Metric-based Early Approach

CLEI Electronic Journal, 2017
Web Services have been steadily gaining maturity as their adoption in the software industry grew. Accordingly, metric suites for assessing different quality attributes of Web Service artifacts have been proposed recently - e.g., for services interfaces ...
Cristian Mateos, Alejandro Zunino, Sanjay Misra, Diego Anabalon, Andrés Flores   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Effects of forest canopy structural complexity on productivity and its stability in the Qinling Mountains: Insights into environmental dependence

Trees, Forests and People
Forest canopy structural complexity is a key determinant of forest productivity and exerts a strong influence on its stability. Yet, the relationship between forest canopy structural complexity and productivity and its stability under changing ...
Chenlu Li, Fei Yu, Tiezhu Jiao, Jiangbo Yan, Xiaohua Feng, Liang Zhao, Arshad Ali, Huiwen Li, Zuoqiang Yuan   +8 more
doaj   +1 more source

Associated Attribute-Aware Differentially Private Data Publishing via Microaggregation

IEEE Access, 2020
Releasing raw data sets with sensitive personal information will leak privacy. Therefore, various differential privacy methods have been proposed for efficient data sharing while preserving privacy.
Gaoming Yang, Xinxin Ye, Xianjin Fang, Rongshi Wu, Li Wang   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Biochemical attributes of mitotic and meiotic presynaptic complexes

DNA Repair, 2018
Homologous recombination (HR) is a universally conserved mechanism used to maintain genomic integrity. In eukaryotes, HR is used to repair the spontaneous double strand breaks (DSBs) that arise during mitotic growth, and the programmed DSBs that form during meiosis.
J Brooks, Crickard, Eric C, Greene
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Using machine learning to predict judgments on Western visual art along content-representational and formal-perceptual attributes.

PLoS ONE
Art research has long aimed to unravel the complex associations between specific attributes, such as color, complexity, and emotional expressiveness, and art judgments, including beauty, creativity, and liking.
Blanca T M Spee, Helmut Leder, Jan Mikuni, Frank Scharnowski, Matthew Pelowski, David Steyrl   +5 more
doaj   +1 more source

An approach for testing the primeness of attributes in relational schemas [PDF]

Computer Science Journal of Moldova, 2009
In this paper there is proposed a method of partition the attributes of relation scheme in equivalence classes and in nonredundant equivalence classes. Several properties of these equivalence classes are proved. Their properties serve as the basis for an
Cotelea Vitalie
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source