Results 81 to 90 of about 915,821 (290)

Impact of Innovations Attributes on e-learning Acceptance among Sri Lankan Postgraduate Students

open access: yesKelaniya Journal of Management, 2014
Though e learning is gaining much popularity in Sri Lanka, the actual and potential users of e-learning facilities possess different perceptions towards the acceptance of e-learning technology.
MRKN Yatigammana   +2 more
doaj   +1 more source

Targeting occasional buyers - the need for quality related communication approaches [PDF]

open access: yes, 2006
Occasional organic buyers often purchase selected organic food items according to perceived added value in terms of quality and food safety issues or perceived additional ecological and social performances along the supply chain. They clearly take a more
Bodini, Antonella   +2 more
core  

A Game of Attribute Decomposition for Software Architecture Design

open access: yes, 2015
Attribute-driven software architecture design aims to provide decision support by taking into account the quality attributes of softwares. A central question in this process is: What architecture design best fulfills the desirable software requirements ...
A Bogomolnaia   +10 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Attribute grammars and automatic complexity analysis

open access: yesAdvances in Applied Mathematics, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Seismic facies classification and TOC prediction using seismic attributes and Hjorth parameters, in the Groningen field in northeastern Netherlands

open access: yesDiscover Applied Sciences
The use of seismic attributes for characterization and exploration is crucial. This significance increases with the growing number of attributes being used, developed, or newly derived, regardless of their relation to previous ones. Facies classification
Reda Al Hasan   +2 more
doaj   +1 more source

Complexity Thinking and Evolutionary Economic Geography [PDF]

open access: yes
Thus far, most of the work towards the construction of an evolutionary economic geography has drawn upon a particular version of evolutionary economics, namely the Nelson-Winter framework, which blends Darwinian concepts and metaphors (especially variety,
Peter Sunley, Ron Martin
core  

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