Results 31 to 40 of about 28,479 (242)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Bridging Problem-Solving and Problem-Posing: Third Graders Learning to Formulate Mathematical Problems in Geometry and Measurement

open access: yesAvances de Investigación en Educación Matemática
This study examines the relationship between problem solving (PS) and problem posing (PP) in mathematics education, focusing on 3rd-graders’ ability to create problems in Geometry and Measurement.
Hugo Fernandes   +2 more
doaj   +1 more source

Selected Remarks about Computer Processing in Terms of Flow Control and Statistical Mechanics

open access: yesEntropy, 2016
Despite the fact that much has been said about processing in computer science, it seems that there is still much to do. A classical approach assumes that the computations done by computers are a kind of mathematical operation (calculations of functions ...
Dominik Strzałka
doaj   +1 more source

Neural mechanisms underlying the computation of hierarchical tree structures in mathematics. [PDF]

open access: yesPLoS ONE, 2014
Whether mathematical and linguistic processes share the same neural mechanisms has been a matter of controversy. By examining various sentence structures, we recently demonstrated that activations in the left inferior frontal gyrus (L.
Tomoya Nakai, Kuniyoshi L Sakai
doaj   +1 more source

Levels of Complexity in Mathematics Teachers’ Knowledge Connections: An Approach Based on MTSK and Piaget’s Schemas

open access: yesEducation Sciences
This paper presents a study whose aim was to formulate a conceptual framework that allows us to understand the degree of complexity of the connections between the knowledge that a mathematics teacher can possess, based on the model of the mathematics teacher’s specialized knowledge model and the Piaget’s schemas.
Estela Juárez-Ruiz   +3 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A generalization of CHSH and the algebraic structure of optimal strategies [PDF]

open access: yesQuantum, 2020
$\textit{Self-testing}$ has been a rich area of study in quantum information theory. It allows an experimenter to interact classically with a black box quantum system and to test that a specific entangled state was present and a specific set of ...
David Cui   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

A systemic approach of urban resilience: power laws and urban growth patterns

open access: yesInternational Journal of Urban Sustainable Development, 2017
Resilient historical cities are the product of evolution and they have been shaped by incremental adaptation to fluctuations and by shocks of various magnitudes.
Serge Salat
doaj   +1 more source

The whole-cell kinetic metabolic model of the pH regulation mechanisms in human erythrocytes

open access: yesRegulatory Mechanisms in Biosystems, 2022
Mathematical modeling in recent years helped to obtain answers to questions that were difficult or even impossible to answer experimentally, to predict several unexpected connections in cell metabolism and to understand and importance of certain ...
O. I. Dotsenko
doaj   +1 more source

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