Results 101 to 110 of about 2,261,092 (281)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Complexity Reduction in Analyzing Independence between Statistical Randomness Tests Using Mutual Information. [PDF]
Entropy (Basel), 2023 Karell-Albo JA +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
IEEE Access, 2019 High-mobility wireless communication systems have attracted growing interests in recent years. For the deployment of these systems, one fundamental work is to build accurate and efficient channel models. In high-mobility scenarios, it has been shown that
Yan Zhang +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A New Exergy Disaggregation Approach for Complexity Reduction and Dissipative Equipment Isolation in Thermoeconomics. [PDF]
Entropy (Basel), 2022 Dos Santos RG +4 more
europepmc +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Complexity reduction and opportunities in the design, integration and intensification of biocatalytic processes for metabolite synthesis. [PDF]
Front Bioeng Biotechnol, 2022 Wohlgemuth R, Littlechild J.
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Toward Questionnaire Complexity Reduction by Decreasing the Questions
Applied SciencesData analysis can unearth important insights like patterns, trends, and deductions. In education, it can be utilized to tailor teaching methods to suit student traits or devise new activities to foster different skills or reinforce existing ones, for ...
Miguel A. Molina-Cabello +3 more
doaj +1 more source