Results 21 to 30 of about 198,491 (146)

EP-173 - EMERGÊNCIA DE UMA LINHAGEM DE ACINETOBACTER BAUMANNII IC2/CC2 CO-PRODUTORA DE OXA-23, NDM-1 E ARMA EM UM HOSPITAL TERCIÁRIO DE SÃO PAULO, BRASIL

Brazilian Journal of Infectious Diseases
Introdução: Acinetobacter baumannii (Acb) é uma das principais bactérias associadas às infecções relacionadas à assistência à saúde, com potencial para aquisição de genes de resistência aos antimicrobianos.
Amanda Yaeko Yamada, Jussimara Monteiro Nurmberger, Fernanda Inoue, Ana Paula Lobo, Cinara Rodrigues Oliveira, Leandro de Lane Moraes, Sérgio Tufik, Simone Quental, Hercília Borges, Carlos Henrique Camargo   +9 more
doaj   +1 more source

RELATO DE CASO: LEUCEMIA MIELOIDE AGUDA MEGACARIOBLÁSTICA COM CARIÓTIPO COMPLEXO EM PACIENTE IDOSA

Hematology, Transfusion and Cell Therapy
Introdução: A leucemia mieloide aguda megacarioblástica (LMA-M7) é uma forma rara de leucemia caracterizada pela proliferação clonal de megacariócitos imaturos.
DSC Filho, LQ Marques, JA Gomes, FM Marques, MDS Pastori, KP Melillo, ET Saito, ABD Manduca, FF Camargo, LLM Perobelli   +9 more
doaj   +1 more source

Studying When to Add Biological Therapy to Cytotoxic Therapy in Advanced Cancer Care Using Real World Data: How to Avoid Design Choices That Generate Immortal Time

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Since real‐world data lack information on treatment assignment (usually the only information available is treatment prescription/administration) and early outcomes can happen in advanced cancer, some design choices may introduce immortal time due to selection or due to treatment strategy misclassification.
Xabier Garcia‐Albeniz, Julia Vila‐Guilera, Manuel Zamparini, Helena Oliveres, Vicente Alonso‐Orduna, Jaime Feliu, Ana Fernández‐Montes, Marta Martín‐Richard, Elisa Gálvez‐Munoz, Ana Ruiz‐Casado, Alfonso Yubero‐Esteban, Jorge Aparicio, Julia Alcaide‐Garcia, Javier Gallego Plazas, Carlos Fernandez‐Martos, Rosa Gallego‐Sanchez, Mónica Guillot Morales, Rubén Leno, Francis Esposito, Sandra Lopez‐Prades, Míriam Cuatrecasas, Barbra A. Dickerman, Joan Maurel   +22 more
wiley   +1 more source

Clonal expansion within pneumococcal serotype 6C after use of seven-valent vaccine [PDF]

, 2013
Streptococcus pneumoniae causes invasive infections, primarily at the extremes of life. A seven-valent conjugate vaccine (PCV7) is used to protect against invasive pneumococcal disease in children.
Nicholas J Loman, Jacqueline Chan, Tocheva Anna S., O’Connor Leigh, Pallen, Mark J., Constantinidou C., Loman, Nicholas J., Pallen M.J., Faust, Saul N, Faust, Saul N., Loman, Nicholas, Clarke S.C., Tocheva A.S., Constantinidou Chrystala, Mark J Pallen, Loman, Nicholas J, Chan, Jacqueline, Constantinidou, Chrystala, Stuart C Clarke, Pallen, Mark J, Gladstone R.A., O'Connor, Leigh, Chrystala Constantinidou, Clarke, Stuart C, Tocheva, Anna S., Faust, S.N., Clarke, S.C., Johanna M C Jefferies, Loman Nicholas J., Faust Saul N., Clarke Stuart C., Gladstone, Rebecca A., Chan J., O’Connor, Leigh, Leigh O'Connor, Anna S Tocheva, Clarke, Stuart C., Pallen, Mark, Tocheva, Anna S, Jefferies J.M.C., Jefferies, Johanna M C, Loman N.J., Chan Jacqueline, Jefferies, Johanna M.C., Gladstone, Rebecca, Saul N Faust, Jefferies Johanna M. C., Jefferies, Johanna M. C., Faust S.N., Pallen Mark J., Gladstone, Rebecca A, Rebecca A Gladstone, O'Connor L., Gladstone Rebecca A.   +53 more
core   +1 more source

Glicosilação 2: complexo de Golgi

, 2016
Ilustra a glicosilação de proteínas acontecendo no complexo de GolgiComponente Curricular::Educação Superior::Ciências Biológicas::Biologia ...
Fundação Centro de Ciências e Educação Superior a Distância do Estado do Rio de Janeiro (CECIERJ)
core   +2 more sources

Freedon study: Real‐life outcomes of cenobamate in different lines of treatment

Epilepsia, Volume 67, Issue 5, Page 2177-2189, May 2026.
Abstract Objectives Cenobamate is an antiseizure medication (ASM) with proven effectiveness in individuals with highly refractory epilepsy. This study investigated the effectiveness and tolerability of cenobamate in different treatment lines and a less refractory setting. Methods This was a multicenter, retrospective, observational study.
Vicente Villanueva, José María Serratosa, Alejandro Fernández‐Cabrera, Manuel Toledo, Beatriz González‐Giráldez, José C. Estevez, Juan Jesús Rodríguez Uranga, Maria Machio Castelló, Maria Dolores Castro‐Vilanova, Juan José Poza, Xiana Rodríguez‐Osorio, Kevin G. Hampel, Elena Fonseca, Francisco Javier López‐González, Mercedes Garcés, Laura Abraira, Jordi Ciurans, Daniel Campos‐Fernández, Estevo Santamarina, Juan María Sanchez‐Caro, Lucas Iacampo, Julia Renau, Miguel Ángel García‐Quesada, Carla Anciones, María Isabel Chamorro, Iratxe Maestro, Pablo Cabezudo, Raquel Calle, Jesús Macarron, Beatriz Cabezas, María Carrasco, María López, Marta Marín, Rosa Querol, Belén Baena, Vanessa García‐Morales, Samuel López‐Maza, Álvaro Juiz, Blanca Mercedes‐Alvarez, Carla Amarante, Ana del Villar, Ascensión Castillo, Marta Rubio‐Roy, Javier Martinez‐Poles, Asier Gómez‐Ibáñez, Beatriz Parejo‐Carbonell, Anabelén Martínez Garcia, Ignacio Carrera, Pablo Iriarte, Fátima Romero‐Aguilera, on behalf of the Pharmacological Therapy Working group of the Spanish Epilepsy Society and Freedon Group   +50 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, Volume 19, Issue 12, Page 3769-3783, December 2025.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

LEUCEMIA MIELOIDE AGUDA SECUNDÁRIA À SÍNDROME MIELODISPLÁSICA COM CARIÓTIPO COMPLEXO E MUTAÇÃO TP53: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Introdução: As Síndromes Mielodisplásicas (SMD) são doenças hematológicas clonais da medula óssea, caracterizadas por produção inadequada de células sanguíneas e alterações na medula óssea.
ML Viana, DPR Porto, LD Napoleão, CC Peixoto, NM Rocha, SBB Duarte, VA Silva, GMB Araújo, MD Magalhães   +8 more
doaj   +1 more source

The human myeloproliferative disorders: molecular pathogenesis and clonal heterogeneity [PDF]

, 2010
The classical myeloproliferative disorders (MPD), comprising essential thrombocythaemia (ET), polycythaemia vera (PV) and idiopathic myelofibrosis (IMF), are clonal premalignant haematopoietic neoplasms associated with activating mutations in signalling ...

core   +2 more sources

INCLUSÕES SEMELHANTES A GRÂNULOS DE SNAPPER-SCHNEID EM PACIENTE COM LEUCEMIA DE CÉLULAS PLASMÁTICAS DURANTE TRATAMENTO NO HEMOCENTRO DO AMAZONAS: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Introdução: A leucemia de células plasmáticas (LCP) é uma neoplasia hematológica linfoproliferativa rara variante do mieloma múltiplo (MM) e pode ser classificada como LCP de novo /primária (LCPp) ou secundária (LCPs).
IC Freitas, JGS Ghedini, JS Moraes, KB Seixas, F Magalhães-Gama, MS Barros, LNM Passos, AM Tarragô, ND Araújo, AG Costa   +9 more
doaj   +1 more source