Results 101 to 110 of about 3,343,238 (342)

Assessment of Anti-Inflammatory and Antioxidant Activities of a Proprietary Preparation of Quercetin–Rutin Blend (SophorOx™) in Exercised Rats

open access: yesThe Scientific World Journal
Objectives. Flavonoids comprise a huge class of phenolic compounds widely distributed throughout the plant kingdom. Although quercetin and rutin have been studied individually for their therapeutic value, the synergistic effect of combining the two has ...
Devanand Shanmugasundaram   +1 more
doaj   +1 more source

Тлумачення в кримінальному праві: особливості та межі

open access: yesНаукові записки НаУКМА: Юридичні науки
У статті розглянуто особливості тлумачення в кримінальному праві, що з огляду на специфіку цієї галузі права є актуальним питанням на сьогодні. Особливу увагу приділено саме розширювальному тлумаченню кримінально-правових норм, що досі викликає гострі ...
Владислав Барильченко
doaj   +1 more source

Compliance and stress sensitivity of spur gear teeth [PDF]

open access: yes, 1983
The magnitude and variation of tooth pair compliance with load position affects the dynamics and loading significantly, and the tooth root stressing per load varies significantly with load position.
Cornell, R. W.
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The significance of artificial intelligence in zero trust technologies: a comprehensive review

open access: yesJournal of Electrical Systems and Information Technology
In the era of cloud computing, cybersecurity has assumed paramount importance. As organizations transition to cloud-based solutions, cyberattackers increasingly target cloud services as a lucrative avenue for unauthorized access to sensitive information.
Deepa Ajish
doaj   +1 more source

Targeting of the Protected Group’s Leadership and Otherwise Representative Members as an Indicator of Genocidal Intent

open access: yesНаукові записки НаУКМА: Юридичні науки
Genocide, i.e., acts committed with the intent to destroy a national, ethnic, religious or racial group, does not require the complete annihilation of every individual member of the group.
Maksym Vishchyk
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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