Results 51 to 60 of about 92,690 (283)
Derivation of Morality from Prudence [PDF]
, 2020 This chapter derives and refines a novel normative moral theory and descriptive theory of moral psychology--Rightness as Fairness--from the theory of prudence defended in Chapter 2.
Arvan, Marcus
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher +8 more
wiley +1 more source
A Subgradient Method for Free Material Design [PDF]
, 2016 A small improvement in the structure of the material could save the manufactory a lot of money. The free material design can be formulated as an optimization problem.
Kocvara, Michal +2 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Chance-Constrained ADMM Approach for Decentralized Control of Distributed Energy Resources
, 2018 Distribution systems are undergoing a dramatic transition from a passive circuit that routinely disseminates electric power among downstream nodes to the system with distributed energy resources.
Chertkov, Michael +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Phenomenological model of elastic distortions near the spin-Peierls transition in $CuGeO_3$
, 1995 A phenomenological model of the Landau type forms the basis for a study of elastic distortions near the spin-Peierls transition $T_c$ in $CuGeO_3$. The atomic displacements proposed by Hirota {\it et al.} [Phys. Rev. Lett.
A.P. Giddy +27 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
On compliance minimization by biomimetic regularization method
Bulletin of the Polish Academy of Sciences Technical SciencesThe standard approach to mechanical design is based on strength hypotheses. However, the structural optimization methods do not take into account this important condition determining the correctness of the engineering solution. The situation is different in the case of biological systems, where reference to material strength is a basic condition for ...
Michał Nowak +3 more
openaire +1 more source