Results 61 to 70 of about 92,690 (283)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Selectivity and minimization: customs control principles

open access: yesLex Portus, 2019
Customs control principles are explored in the article, particularly, minimization and selectivity principles. Customs control is believed to be one of the main operations, its quality procedure influences on the compliance with the customs legislation ...
Harmash Alina
doaj   +1 more source

Mathematical Model of Vaccine Noncompliance [PDF]

open access: yes, 2016
Vaccine scares can prevent individuals from complying with a vaccination program. When compliance is high, the critical vaccination proportion is close to being met, and herd immunity occurs, bringing the disease incidence to extremely low levels.
Bauer, Jordan, Capaldi, Alex
core   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Blockchain Technology and GDPR Compliance: A Comprehensive Applicability Model [PDF]

open access: yesInternational Journal of Web Research
This study investigates the potential of blockchain technology to support compliance with the General Data Protection Regulation (GDPR). By integrating blockchain's core features, such as transparency, immutability, and data encryption, with GDPR ...
Abouzar Arabsorkhi , Elham Khazaei
doaj   +1 more source

Advanced Cloud Privacy Threat Modeling

open access: yes, 2016
Privacy-preservation for sensitive data has become a challenging issue in cloud computing. Threat modeling as a part of requirements engineering in secure software development provides a structured approach for identifying attacks and proposing ...
Gholami, Ali, Laure, Erwin
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Lymphocyte-depleting induction and steroid minimization after kidney transplantation: A review

open access: yesNefrología (English Edition), 2016
Steroid minimization after kidney transplantation has become more widely practiced as transplant clinicians seek the potential benefits such as reduced cardiovascular risk factors, improved growth in pediatric patients, and improved compliance with the ...
Maarten Naesens   +9 more
doaj   +3 more sources

TOPOLOGY OPTIMIZATION DESIGN METHOD FOR HINGE-FREE MULTI-INPUT MULTI-OUTPUT COMPLIANT MECHANISMS UNDER BUCKLING CONSTRAINTS (MT)

open access: yesJixie qiangdu, 2022
In view of stability requirements of compliant mechanisms, based on the Heaviside three-field mapping scheme and the compliance change rate constraint measure, the topology optimization problem of the compliance minimization of hinge-free multi-input ...
GAN Wei   +5 more
doaj  

Developing Risk Management Mechanism at Fat-and-Oil Industry Enterprises [PDF]

open access: yes, 2019
The aim of the article is consideration of questions associated with the risk management mechanism formation at the Ukrainian fat-and-oil industry enterprises, modern scientific publications on this topical subject and developing risk management ...
Korin, Myroslava   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy