Results 101 to 110 of about 8,022,362 (339)

Lubrication model of a knee prosthesis, with non newtonian fluid and porous rough material [PDF]

, 2009
Tibial component of knee prostheses, made of ultra high molecular weight polyethylene (UHMWPE), experiences a high degree of wear and may be expected to last twelve years on average.
Berli, Marcelo Eduardo, Campana, Diego Martin, Di Paolo, José, Ubal, Sebastian   +3 more
core  

Cellular Helmet Liner Design through Bio-inspired Structures and Topology Optimization of Compliant Mechanism Lattices

, 2018
The continuous development of sport technologies constantly demands advancements in protective headgear to reduce the risk of head injuries. This article introduces new cellular helmet liner designs through two approaches. The first approach is the study
Joel C. Najmon, J. Dehart, Zebulun M. Wood, A. Tovar   +3 more
semanticscholar   +1 more source

A Lamina-Emergent Frustum Using a Bistable Collapsible Compliant Mechanism

Journal of Mechanical Design, 2018
This paper presents a new bistable collapsible compliant mechanism (BCCM) that is utilized in a lamina-emergent frustum. The mechanism is based on transforming a polygon spiral into spatial frustum shape using a mechanism composed of compliant links and ...
Rami Alfattani, C. Lusk
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Design and Analysis of a Fully Compliant Micro-gripper based on Hinge Stiffness

Jixie chuandong, 2016
The compliant micro- gripper is kind of mechanism used to amplify and transfer the micro-actuators displacement. The compliant mechanism accomplishes the transmission or transformation of motion,force and energy by the deformation of flexible components ...
Deng Zilong, Gao Jinhai
doaj  

Hot lamination and origami assembly fabrication of miniaturized compliant mechanism. [PDF]

MethodsX, 2021
Ozaki T, Ohta N, Fujiyoshi M.
europepmc   +1 more source

Systems and Methods for Implementing Bulk Metallic Glass-Based Macroscale Compliant Mechanisms [PDF]

Systems and methods in accordance with embodiments of the invention implement bulk metallic glass-based macroscale compliant mechanisms. In one embodiment, a bulk metallic glass-based macroscale compliant mechanism includes: a flexible member that is ...
Agnes, Gregory, Hofmann, Douglas C.
core   +1 more source