Results 91 to 100 of about 1,600,826 (295)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Three‐dimensional body composition parameters using automatic volumetric segmentation allow accurate prediction of colorectal cancer outcomes

Journal of Cachexia, Sarcopenia and Muscle
Background Parameters obtained from two‐dimensional (2D) cross‐sectional images have been used to determine body composition. However, data from three‐dimensional (3D) volumetric body images reflect real body composition more accurately and may be better
Aiya Bimurzayeva, Min Jung Kim, Jong‐Sung Ahn, Ga Yoon Ku, Dokyoon Moon, Jinsun Choi, Hyo Jun Kim, Han‐Ki Lim, Rumi Shin, Ji Won Park, Seung‐Bum Ryoo, Kyu Joo Park, Han‐Jae Chung, Jong‐Min Kim, Sang Joon Park, Seung‐Yong Jeong   +15 more
doaj   +1 more source

Hemobilia due to cystic artery pseudoaneurysm: A rare late complication of laparoscopic cholecystectomy [PDF]

, 2017
We discuss a patient with late presentation of hemobilia following cholecystectomy, which is unusual because pseudoaneurysm caused by vascular injury during surgery typically presents soon after surgery.
Badillo, Ricardo, Darcy, Michael D, Kushnir, Vladimir M   +2 more
core   +2 more sources

Blepharoplasty Complications [PDF]

Facial Plastic Surgery, 2012
There are three major areas of concern for a patient who has complications following a cosmetic blepharoplasty: cosmetic issues, functional issues, and uncomfortable/symptomatic issues or a combination of the above. An emphasis will be placed on avoiding cosmetic eyelid complications as well as the medical and surgical management of complications.
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Intrauterine death from placental abruption: influence of labor duration and mode of delivery on maternal outcomes

Frontiers in Medicine
IntroductionIntrauterine fetal death (IUFD) caused by retroplacental hematoma (RPH) can lead to serious maternal complications including coagulopathies and hemorrhage. A prolonged diagnostic-to-expulsion delay may increase coagulation risks.
Louis Van Hees, Louis Van Hees, Robin Danger, Caroline Turbelin, Caroline Turbelin   +4 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Managing the Complex Patient with Degenerative Cervical Myelopathy: How to Handle the Aging Spine, the Obese Patient, and Individuals with Medical Comorbidities. [PDF]

, 2018
Degenerative cervical myelopathy (DCM) is the most common cause of nontraumatic spinal cord injury worldwide. Even relatively mild impairment in functional scores can significantly impact daily activities.
Gillick, John, Harrop, James, Rymarczuk, George, Stricsek, Geoffrey   +3 more
core   +1 more source

Characteristic and Correlation Between TIME and Complication After Destructive Eye Procedure Patient at Plastic and Reconstruction Division Sanglah Hospital\u27s Eye Clinic Bali-Indonesia [PDF]

, 2012
Destructive eye procedure can be carried out by enucleation, evisceration and excenteration. Some efforts have been developed to reduce the complications, but it still occur within several years after the operation.
Sukartini, D. (D), Triharpini, N. (N), Yuliawati, P. (P)   +2 more
core   +2 more sources