Results 91 to 100 of about 1,152,883 (314)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An Unusual Acute Otitis Media Complication: Luc’s Abscess [PDF]
Otitis media, a common childhood disease, can lead to serious complications such as acute mastoiditis and, rarely, Luc’s abscess, with life-threatening consequences. Luc’s abscess, a rare but severe complication, can occur without acute mastoiditis. This
Meltem Akpınar, Beyza Demirci
core +1 more source
Frontiers in MedicineIntroductionIntrauterine fetal death (IUFD) caused by retroplacental hematoma (RPH) can lead to serious maternal complications including coagulopathies and hemorrhage. A prolonged diagnostic-to-expulsion delay may increase coagulation risks.
Louis Van Hees +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2023 Purpose of this study was to compare the complication rates between reverse-tapered and nontapered peripherally inserted central catheters (PICCs).
Hyun Soo Bae (15411910) +2 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Hydrothorax with Atypical Features as a Complication of Peritoneal Dialysis: A Case Report and Literature Review [PDF]
, 2023 Hydrothorax is an uncommon but established complication of peritoneal dialysis, usually arising from pleuroperitoneal leak. There is currently no consensus on definitive testing or management.
Ankur D Shah, Aaron Wang, Susie L Hu
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Profile of Chronic Suppurative Otitis Media Complication in Indonesian Patients: Review of 25 Cases [PDF]
, 2020 Background: The number of CSOM complications is increasing every year, especially in developing countries. Indonesia is a developing country with a large population and a large number of CSOM cases. Objectives: Analysing the profile of CSOM patients with
Rosyidiah Rahmawati, - +3 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
, 2018 Yi Ji,1 Kaiying Yang,1 Siyuan Chen,2 Suhua Peng,1 Guoyan Lu,3 Xingtao Liu4 1Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China; 2Pediatric Intensive Care Unit, Department of Critical Care ...
Liu X +5 more
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