Results 91 to 100 of about 4,251,609 (342)

The Renoprotective Actions of Peroxisome Proliferator-Activated Receptors Agonists in Diabetes

open access: yesPPAR Research, 2012
Pharmaceutical agonists of peroxisome proliferator-activated receptors (PPARs) are widely used in the management of type 2 diabetes, chiefly as lipid-lowering agents and oral hypoglycaemic agents.
M. C. Thomas   +2 more
doaj   +1 more source

Complications of percutaneous endoscopic gastrostomy in dogs and cats receiving corticosteroid treatment [PDF]

open access: yes, 2016
BACKGROUND: Corticosteroid treatment is commonly required in veterinary patients for treatment of inflammatory, immune‐mediated, neurologic, and neoplastic diseases, which also may require assisted enteral nutrition via percutaneous endoscopic ...
Aguiar, J, Chang, Y M, Garden, O A
core   +1 more source

Fast, Automated, Knowledge-Based Treatment Planning for Selecting Patients for Proton Therapy Based on Normal Tissue Complication Probabilities [PDF]

open access: gold, 2022
Roni Hytönen   +5 more
openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Motivation to Prevent Chronic Disease or Complications [PDF]

open access: yes, 2019
Motivational interviewing has been used with relatively positive success in behavioral interventions as a way to stimulate change in patient\u27s habits and attitudes, yet there is little information available as to how to design and implement a plan of ...
Pike, Ashton Hideki
core   +1 more source

Osteomalacia as a Complication of Intravenous Iron Infusion: A Systematic Review of Case Reports [PDF]

open access: hybrid, 2020
Tatiane Vilaça   +4 more
openalex   +1 more source

Comparison of infectious complications after spleen preservation versus splenectomy during laparoscopic distal pancreatectomy for benign or low‐grade malignant pancreatic tumors: A multicenter, propensity score‐matched analysis [PDF]

open access: bronze, 2022
Woohyung Lee   +35 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

PPAR Agonists and Cardiovascular Disease in Diabetes

open access: yesPPAR Research, 2008
Peroxisome proliferators activated receptors (PPARs) are ligand-activated nuclear transcription factors that play important roles in lipid and glucose homeostasis.
Anna C. Calkin, Merlin C. Thomas
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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