Results 111 to 120 of about 6,001,301 (391)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Complications of Diabetes 2017

Journal of Diabetes Research, 2018
Outpatient Clinic of Diabetes, University Hospital of Alexandroupolis, Alexandroupolis, Greece Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Łódź, Poland Diabetes Center and Second Medical Department ...
K. Papatheodorou, M. Banach, E. Bekiari, M. Rizzo, M. Edmonds   +4 more
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Rare Complications of Cervical Spine Surgery: Pseudomeningocoele. [PDF]

, 2017
STUDY DESIGN: This study was a retrospective, multicenter cohort study. OBJECTIVES: Rare complications of cervical spine surgery are inherently difficult to investigate.
Ailon, Tamir, Arnold, Paul M., Buser, Zorica, Chou, Dean, Corriveau, Mark, Fehlings, Michael G., Fish, David E., Hilibrand, Alan S., Hsu, Wellington K., Lee, Sungho, Lord, Elizabeth L L., Massicotte, Eric M., Mroz, Thomas E., Mummaneni, Praveen V., Nassr, Ahmad, Pace, Jonathan, Riew, K. Daniel, Sasso, Rick C., Sebastian, Arjun S., Shaffrey, Christopher, Smith, Gabriel A., Smith, Justin S., Smith, Zachary A., Steinmetz, Michael P., Than, Khoi D., Traynelis, Vincent C., Wang, Jeffrey C.   +26 more
core   +2 more sources

Benchmarking Complications Associated with Esophagectomy

Annals of Surgery, 2017
Objective: Utilizing a standardized dataset with specific definitions to prospectively collect international data to provide a benchmark for complications and outcomes associated with esophagectomy.
D. Low, M. Kuppusamy, D. Alderson, I. Cecconello, A. Chang, G. Darling, A. Davies, X. D’Journo, S. Gisbertz, M. Griffin, R. Hardwick, A. Hoelscher, W. Hofstetter, B. Jobe, Y. Kitagawa, S. Law, C. Mariette, N. Maynard, C. Morse, P. Nafteux, M. Pera, C. Pramesh, S. Puig, J. Reynolds, W. Schroeder, M. Smithers, B. Wijnhoven   +26 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Insulin's actions on vascular tissues: Physiological effects and pathophysiological contributions to vascular complications of diabetes

Molecular Metabolism, 2021
Background: Insulin has been demonstrated to exert direct and indirect effects on vascular tissues. Its actions in vascular cells are mediated by two major pathways: the insulin receptor substrate 1/2-phosphoinositide-3 kinase/Akt (IRS1/2/PI3K/Akt ...
Jialin Fu, Marc Gregory Yu, Qian Li, Kyoungmin Park, George L. King   +4 more
doaj  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories”

EBioMedicine, 2016
The directed differentiation of human cardiomyocytes (CMs) from pluripotent cells provides an invaluable model for understanding mechanisms of cell fate determination and offers considerable promise in cardiac regenerative medicine.
Joshua D. Tompkins, Marc Jung, Chang-yi Chen, Ziguang Lin, Jingjing Ye, Swetha Godatha, Elizabeth Lizhar, Xiwei Wu, David Hsu, Larry A. Couture, Arthur D. Riggs   +10 more
doaj   +1 more source

A systematic review of ICD complications in randomised controlled trials versus registries: is our 'real-world' data an underestimation? [PDF]

, 2015
Implantable cardioverter defibrillator (ICD) implantation carries a significant risk of complications, however published estimates appear inconsistent. We aimed to present a contemporary systematic review using meta-analysis methods of ICD complications ...
Ahsan, S, Chow, AW, Ezzat, VA, Lambiase, PD, Lee, V, Lowe, MD, Rowland, E, Segal, O   +7 more
core   +2 more sources