Results 11 to 20 of about 6,001,301 (391)
Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown.
Vishnu Amaram Samara+9 more
doaj +1 more source
A cohort study of membranous nephropathy, primary or secondary
Background Although IgG4 deposit against phospholipase A2 receptor (anti-PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous nephropathy (MN), its diagnostic value of this immune complex has not been fully ...
Maryam Arghiani+7 more
doaj +1 more source
Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT [PDF]
BackgroundEpithelial-to-mesenchymal transition (EMT) is required for renal fibrosis, which is a characteristic of diabetic nephropathy (DN). Our previous study demonstrated that fibroblast growth factor 21 (FGF21) prevented DN associated with the ...
Sundong Lin+6 more
doaj +1 more source
BackgroundRoux-en-Y gastric bypass surgery (RYGB) improves biochemical and histological parameters of diabetic kidney disease (DKD). Targeted adjunct medical therapy may enhance renoprotection following RYGB.MethodsThe effects of RYGB and RYGB plus ...
William P. Martin+12 more
doaj +1 more source
Complications of Diabetes [PDF]
Diabetes is justly recognized as an emerging global epidemic, representing one of the leading causes of morbidity and mortality worldwide. Hyperglycemia, the common characteristic of both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM), has the potential to cause serious complications due to its insidious and chronic nature.
Konstantinos Papatheodorou+4 more
openaire +4 more sources
Complicated or Non-complicated Appendicitis? That is the Question
Acute appendicitis (AA) is a common disease that includes all age groups and both genders in societies and is one of the most common causes of acute abdomen. It is important to distinguish between complicated and non-complicated appendicitis before surgery.
Dinç, Tolga+3 more
openaire +3 more sources
In patients with diabetes, it has been suggested that physical exercise may reduce albuminuria and the progression of renal disease. However, the molecular mechanism by which physical exercise protects the kidney in diabetes remains poorly understood ...
Guilherme Pedron Formigari+6 more
doaj +1 more source
Endogenous FGF1 Deficiency Aggravates Doxorubicin-Induced Hepatotoxicity
Doxorubicin (DOX) is a broad-spectrum antineoplastic agent that widely used in clinic. However, its application is largely limited by its toxicity in multiple organs. Fibroblast growth factor 1 (FGF1) showed protective potential in various liver diseases,
Chunjie Gu+9 more
doaj +1 more source
Complications of frontal defects [PDF]
A case where the severe course of an orbital phlegmon led to a functionally and cosmetically poor condition is presented. Thirty-five years later, it was possible to achieve a satisfactory result through several operations performed with ...
Berghaus, Alexander, Schmidt, B.
core +1 more source
In-depth critical analysis of complications following robot-assisted radical cystectomy with intracorporeal urinary diversion [PDF]
Background: Robot-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) is an attractive option to open cystectomy, but the benefit in terms of improved outcomes is not established.
Ahmad, Imran+9 more
core +2 more sources