Results 11 to 20 of about 2,084,056 (269)
Communications Biology, 2021 Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1 ...
Mitsuo Kato +14 more
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A cohort study of membranous nephropathy, primary or secondary
BMC Nephrology, 2021 Background Although IgG4 deposit against phospholipase A2 receptor (anti-PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous nephropathy (MN), its diagnostic value of this immune complex has not been fully ...
Maryam Arghiani +7 more
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Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT [PDF]
Diabetes & Metabolism Journal, 2020 BackgroundEpithelial-to-mesenchymal transition (EMT) is required for renal fibrosis, which is a characteristic of diabetic nephropathy (DN). Our previous study demonstrated that fibroblast growth factor 21 (FGF21) prevented DN associated with the ...
Sundong Lin +6 more
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Frontiers in Endocrinology, 2022 BackgroundRoux-en-Y gastric bypass surgery (RYGB) improves biochemical and histological parameters of diabetic kidney disease (DKD). Targeted adjunct medical therapy may enhance renoprotection following RYGB.MethodsThe effects of RYGB and RYGB plus ...
William P. Martin +12 more
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Vertical sleeve gastrectomy reverses diet-induced gene-regulatory changes impacting lipid metabolism
Scientific Reports, 2017 Vertical sleeve gastrectomy (VSG) produces sustainable weight loss, remission of type 2 diabetes (T2D), and improvement of nonalcoholic fatty liver disease (NAFLD).
Juan Du +7 more
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Endogenous FGF1 Deficiency Aggravates Doxorubicin-Induced Hepatotoxicity
Toxics, 2023 Doxorubicin (DOX) is a broad-spectrum antineoplastic agent that widely used in clinic. However, its application is largely limited by its toxicity in multiple organs. Fibroblast growth factor 1 (FGF1) showed protective potential in various liver diseases,
Chunjie Gu +9 more
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Assessment of Risk Factors for Hospital Readmission after Kidney Transplantation
علوم بهداشتی ایران, 2021 Background and Purpose: Hospital readmission after kidney transplantation is a real challenge for both patients and healthcare systems. Assessment of the risk factors of readmission after kidney transplantation is vital and can reduce morbidity and cost ...
Mahmoud Tavakkoli +5 more
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Scientific Reports, 2022 In patients with diabetes, it has been suggested that physical exercise may reduce albuminuria and the progression of renal disease. However, the molecular mechanism by which physical exercise protects the kidney in diabetes remains poorly understood ...
Guilherme Pedron Formigari +6 more
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Cellular and Molecular Gastroenterology and Hepatology, 2022 Background & Aims: Alcohol-associated liver disease (AALD) is one of the most common causes of liver injury and failure. Limited knowledge of the mechanisms underlying AALD impedes the development of efficacious therapies.
Mingjie Fan +15 more
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BMJ Case Reports, 2023 We present the case of a woman in her late 20s who consulted our gynaecology emergency department due to dyspareunia and vaginal penetration issues. She had undergone a ‘virginity reconstruction’ procedure 10 days before her wedding in Africa. Clinical examination revealed suture of the inferior part of inner labia (labia minora), narrowing of the ...
Pace, Margherita +3 more
openaire +3 more sources